Evidence map›Paper›PMID 28003147›Full record

ArticleJournal of biomedical informatics2017

Developing the Quantitative Histopathology Image Ontology (QHIO): A case study using the hot spot detection problem.

Metin N Gurcan, John Tomaszewski, James A Overton, Scott Doyle, Alan Ruttenberg, Barry Smith

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Artificial intelligence driven next-generation renal histomorphometry.Current opinion in nephrology and hypertension · 2020
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Metin N GurcanDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH 43210, USA. Electronic address: metin.gurcan@osumc.edu.
John TomaszewskiDepartment of Pathology and Anatomical Sciences, University at Buffalo, Buffalo, NY 14214, USA.
James A OvertonKnocean Inc., Toronto, Ontario M6P 2T3, Canada.
Scott DoyleDepartment of Pathology and Anatomical Sciences, University at Buffalo, Buffalo, NY 14214, USA.
Alan RuttenbergSchool of Dental Medicine, University at Buffalo, Buffalo NY, 14214, USA.
Barry SmithDepartment of Philosophy, University at Buffalo, Buffalo, NY 14260, USA.

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
PRO: A Protein Ontology in Open Biomedical OntologiesR01GM080646 · NIGMS · UNIVERSITY OF DELAWARE · PI WU, CATHY H. · 2007 to 2018
$8.9M
Pathology Image Informatics Platform for visualization, analysis and managementU24CA199374 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI GURCAN, METIN NAFI, MADABHUSHI, ANANT · 2015 to 2019
$2.9M
Computer-based assessment of tumor microenvironment (TME) in Follicular LymphomaR01CA134451 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI GURCAN, METIN NAFI, LOZANSKI, GERARD · 2009 to 2017
$2.3M
NCATS NIH HHS UL1 TR001412NCI NIH HHS R01 CA134451NCI NIH HHS U24 CA199374NIGMS NIH HHS R01 GM080646
6 · The paper itself

Abstract

Interoperability across data sets is a key challenge for quantitative histopathological imaging. There is a need for an ontology that can support effective merging of pathological image data with associated clinical and demographic data. To foster organized, cross-disciplinary, information-driven collaborations in the pathological imaging field, we propose to develop an ontology to represent imaging data and methods used in pathological imaging and analysis, and call it Quantitative Histopathological Imaging Ontology - QHIO. We apply QHIO to breast cancer hot-spot detection with the goal of enhancing reliability of detection by promoting the sharing of data between image analysts.

Indexed as

Biological OntologiesHistologyHumansPathologyReproducibility of ResultsBreast cancerHistopathology imagingHot spotImage analysisOntology

Identifiers

PMID28003147
PMCPMC5316345

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.