Evidence map›Paper›PMID 28002685›Full record

Trial reportApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2017

Effects of blood-flow restriction on biomarkers of myogenesis in response to resistance exercise.

Andrew S Layne, Kelly Larkin-Kaiser, R Gavin MacNeil, Marvin Dirain, Bhanuprasad Sandesara, Todd M Manini, Thomas W Buford

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Frontiers in medicine · 2019
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew S Laynea University of Florida, 2004 Mowry Rd. Gainesville, FL 32611, USA.
Kelly Larkin-Kaiserb University of Calgary, 2500 University Drive NW. Calgary, AB T2N 1N4, Canada.
R Gavin MacNeilc NOVA Southeastern Medical School, 3301 College Ave. Fort Lauderdale, FL 33314, USA.
Marvin Diraina University of Florida, 2004 Mowry Rd. Gainesville, FL 32611, USA.
Bhanuprasad Sandesaraa University of Florida, 2004 Mowry Rd. Gainesville, FL 32611, USA.
Todd M Maninia University of Florida, 2004 Mowry Rd. Gainesville, FL 32611, USA.
Thomas W Buforda University of Florida, 2004 Mowry Rd. Gainesville, FL 32611, USA.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Marco Pahor · 2007 to 2026
$22.8M
UF CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR029890 · NCRR · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2009 to 2011
$14.4M
UF Clinical and Translational Science AwardKL2RR029888 · NCRR · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2009 to 2011
$1.8M
NCATS NIH HHS UL1 TR001427NCRR NIH HHS KL2 RR029888NCRR NIH HHS UL1 RR029890NIA NIH HHS P30 AG028740
6 · The paper itself

Abstract

We investigated the acute myogenic response to resistance exercise with and without blood-flow restriction (BFR). Six men and women (age, 22 ± 1 years) performed unilateral knee extensions at 40% of 1-repetition maximum with or without (CNTRL) BFR applied via pressure cuff inflated to 220 mm Hg. Muscle biopsies were collected at 4 h and 24 h postexercise. Addition of BFR increased myoD and c-Met messenger RNA expression relative to CNTRL. Expression of hepatocyte growth factor protein was significantly higher following CNTRL.

Indexed as

Muscle DevelopmentUp-RegulationAdolescentAdultBiomarkersBiopsy, NeedleConstrictionCross-Over StudiesFemaleGene Expression RegulationHepatocyte Growth FactorHumansMaleMyoD ProteinProto-Oncogene Proteins c-metQuadriceps MuscleBiomarkersHepatocyte Growth FactorHGF protein, humanMET protein, humanMyoD ProteinProto-Oncogene Proteins c-metRNA, Messengerblood flow restrictionexercice contre résistancefacteur de croissance des hépatocyteshepatocyte growth factorKAATSUmuscle squelettiquemyogenèsemyogenesisresistance exerciserestriction du débit sanguinskeletal muscle

Identifiers

PMID28002685
PMCPMC6151869

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.