ArticlePloS one2016
Mass Density Measurement of Mineralized Tissue with Grating-Based X-Ray Phase Tomography.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Mandible bone mineral density estimation using spectral panoramic X-ray imaging.Imaging science in dentistry · 2025Article
- Stannous Fluoride in Toothpastes: A Review of Its Clinical Effects and Likely Mechanisms of Action.Journal of functional biomaterials · 2025Review
- Multidisciplinary evaluation of the remineralization potential of three fluoride-based toothpastes on natural white spot lesions.Clinical oral investigations · 2023Article
- Synchrotron X-ray Studies of the Structural and Functional Hierarchies in Mineralised Human Dental Enamel: A State-of-the-Art Review.Dentistry journal · 2023Review
- Miscibility and Optimization of the Liquid Rubber Content in the Resins of Light-Cured Dental Composites.Materials (Basel, Switzerland) · 2022Article
- Adaptive Mechanism for Designing a Personalized Cranial Implant and Its 3D Printing Using PEEK.Polymers · 2022Article
- The Development of Dentin Microstructure Is Controlled by the Type of Adjacent Epithelium.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022Article
- Prevention of Caries and Dental Erosion by Fluorides-A Critical Discussion Based on Physico-Chemical Data and Principles.Dentistry journal · 2022Review
- Enamel and dentin in Enamel renal syndrome: A confocal Raman microscopy view.Frontiers in physiology · 2022Article
- Quantitative X-ray phase contrast computed tomography with grating interferometry : Biomedical applications of quantitative X-ray grating-based phase contrast computed tomography.European journal of nuclear medicine and molecular imaging · 2021Review
- Fast X-ray Differential Phase Contrast Imaging with One Exposure and without Movements.Scientific reports · 2019Article
- Characterization of enamel caries lesions in rat molars using synchrotron X-ray microtomography.Journal of synchrotron radiation · 2017Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Establishing the mineral content distribution in highly mineralized tissues, such as bones and teeth, is fundamental in understanding a variety of structural questions ranging from studies of the mechanical properties to improved pathological investigations. However, non-destructive, volumetric and quantitative density measurements of mineralized samples, some of which may extend several mm in size, remain challenging. Here, we demonstrate the potential of grating-based x-ray phase tomography to gain insight into the three-dimensional mass density distribution of tooth tissues in a non-destructive way and with a sensitivity of 85 mg/cm3. Density gradients of 13 - 19% over 1 - 2 mm within typical samples are detected, and local variations in density of 0.4 g/cm3 on a length scale of 0.1 mm are revealed. This method proves to be an excellent quantitative tool for investigations of subtle differences in mineral content of mineralized tissues that can change following treatment or during ageing and healing.
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