Evidence map›Paper›PMID 28001313›Full record

ArticleVox sanguinis2017

Incidence and clinical characteristics of transfusion-associated circulatory overload using an active surveillance algorithm.

N H Roubinian, J E Hendrickson, D J Triulzi, J L Gottschall, D Chowdhury, D J Kor, M R Looney, M A Matthay, S H Kleinman, D Brambilla and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vox sanguinis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. New frontiers in neonatal red blood cell transfusion research.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. TACO and TRALI: biology, risk factors, and prevention strategies.Hematology. American Society of Hematology. Education Program · 2018
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

N H RoubinianBlood Systems Research Institute, San Francisco, CA, USA.
J E HendricksonYale University, New Haven, CT, USA.
D J TriulziInstitute For Transfusion Medicine, Pittsburgh, PA, USA.
J L GottschallBloodCenter of Wisconsin, Milwaukee, WI, USA.
D ChowdhuryRTI International, Rockville, MD, USA.
D J KorMayo Clinic, Rochester, MN, USA.
M R LooneyUniversity of California, San Francisco, CA, USA.
M A MatthayUniversity of California, San Francisco, CA, USA.
S H KleinmanUniversity of British Columbia, Victoria, BC, Canada.
D BrambillaRTI International, Rockville, MD, USA.
E L MurphyBlood Systems Research Institute, San Francisco, CA, USA.
NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III)

Funding

NHLBI NIH HHS HHSN268201000002CNHLBI NIH HHS HHSN268201000003CNHLBI NIH HHS HHSN268201000004CNHLBI NIH HHS HHSN268201000005CNHLBI NIH HHS HHSN268201100002INHLBI NIH HHS HHSN268201100003INHLBI NIH HHS HHSN268201100004INHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS L30 HL129355WHI NIH HHS HHSN268201100002CWHI NIH HHS HHSN268201100003CWHI NIH HHS HHSN268201100004C
6 · The paper itself

Abstract

backgroundThe concordance of haemovigilance criteria developed for surveillance of transfusion-associated circulatory overload (TACO) with its clinical diagnosis has not been assessed. In a pilot study to evaluate an electronic screening algorithm, we sought to examine TACO incidence and application of haemovigilance criteria in patients with post-transfusion pulmonary oedema. STUDY DESIGN AND

methodsFrom June to September 2014, all transfused adult inpatients at four academic hospitals were screened with an algorithm identifying chest radiographs ordered within 12 h of blood component release. Patients with post-transfusion pulmonary oedema underwent case adjudication by an expert panel. TACO incidence was calculated, and clinical characteristics were compared with other causes of post-transfusion pulmonary oedema.

resultsAmong 4932 transfused patients, there were 3412 algorithm alerts, 50 cases of TACO and 47 other causes of pulmonary oedema. TACO incidence was 1 case per 100 patients transfused. TACO classification based on two sets of haemovigilance criteria (National Healthcare Safety Network and proposed revised International Society for Blood Transfusion) was concordant with expert panel diagnosis in 57% and 54% of reviewed cases, respectively. Although the majority of clinical parameters did not differentiate expert panel adjudicated TACO from other cases, improved oxygenation within 24 h of transfusion did (P = 0·01).

conclusionsThe incidence of TACO was similar to that observed in prior studies utilizing active surveillance. Case classification by haemovigilance criteria was frequently discordant with clinical diagnoses of TACO in patients with post-transfusion pulmonary oedema. Improvements in oxygenation within 24 h of transfusion merit further evaluation in the diagnosis of TACO.

Indexed as

AlgorithmsTransfusion ReactionAcute Lung InjuryAdultAgedAged, 80 and overFemaleHospitals, UniversityHumansIncidenceMaleMiddle AgedPulmonary EdemaRetrospective StudiesRisk FactorsTreatment Outcome

Identifiers

PMID28001313
PMCPMC5257198

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.