Evidence map›Paper›PMID 28000443›Full record

ArticleEnvironmental science & technology2017

Predictors of Serum Polybrominated Diphenyl Ether (PBDE) Concentrations among Children Aged 1-5 Years.

Lyndsey A Darrow, Melanie H Jacobson, Emma V Preston, Grace E Lee, Parinya Panuwet, Ronald E Hunter, M Elizabeth Marder, Michele Marcus, Dana B Barr

Abstract read
In one paragraph

Article in Environmental science & technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
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  6. Article
  7. Article
  8. Article
  9. Exposure to flame retardants in European children - Results from the HBM4EU aligned studies.International journal of hygiene and environmental health · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Brominated Flame Retardants in Children's Room: Concentration, Composition, and Health Risk Assessment.International journal of environmental research and public health · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lyndsey A DarrowSchool of Community Health Sciences, University of Nevada , Reno, Nevada 89557, United States.ORCID 0000-0002-0137-8975
Melanie H Jacobson
Emma V PrestonDepartment of Environmental Health, Boston University School of Public Health , Boston, Massachusetts 02118, United States.
Grace E LeeBattelle Memorial Institute , Atlanta, Georgia 30329, United States.
Parinya Panuwet
Ronald E Hunter
M Elizabeth Marder
Michele Marcus
Dana B Barr
Battelle · USBoston University · USUniversity of Nevada, Reno · US

Funding

Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
Graduate and Postdoctoral Training in ToxicologyT32ES012870 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit · 2004 to 2026
$9.1M
PBDE Body Burdens, House Dust Concentrations and Associations with Thyroid HormonR21ES019697 · NIEHS · EMORY UNIVERSITY · PI BARR, DANA BOYD, DARROW, LYNDSEY · 2011 to 2012
$433k
NIEHS NIH HHS P30 ES019776NIEHS NIH HHS R21 ES019697NIEHS NIH HHS T32 ES012870
6 · The paper itself

Abstract

Serum concentrations of PBDEs were measured using gas chromatography-tandem mass spectrometry in 80 children aged 15-71 months. Demographic and behavioral data were collected on parental questionnaires; a research nurse recorded anthropometric measures and insurance status. For a subset of children (n = 17), PBDEs were measured in house dust and child handwipes sampled during a home visit. In linear and Tobit regression, log-transformed PBDE congeners were modeled as a function of child characteristics, including neighborhood-level socioeconomic indicators. BDE congeners 47, 99, and 100 were highly correlated and summed for analysis; BDE-153 was examined individually. PBDE serum concentrations were associated with socioeconomic factors; for example, a $20,000 increase in median household income in a child's ZIP code was associated with a 34% decrease (95%CI = 14-49%) in BDE-153 and a 26% decrease (95%CI = 6-42%) in ∑BDE-47,-99,-100. Lower body-mass index (BMI) z-score and household smoking were strong predictors of higher BDE-153 levels. Among children who participated in a home visit, serum PBDE was positively correlated with handwipe PBDE (Spearman r ∑BDE-47, -99, -100 = 0.48, p = 0.09), but not dust PBDE. Results indicate socioeconomic factors and BMI are strong predictors of serum PBDE levels among young children. PBDEs measured on handwipes are more predictive of serum PBDE levels than vacuum-collected dust.

Indexed as

DustHalogenated Diphenyl EthersChild, PreschoolHumansInfantSmokingSocioeconomic FactorsSurveys and QuestionnairesDustHalogenated Diphenyl Ethers

Identifiers

PMID28000443
PMCPMC5538570
OpenAlexW2564575407

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.