ArticleObesity (Silver Spring, Md.)2017
Anxiety independently contributes to elevated inflammation in humans with obesity.
Article in Obesity (Silver Spring, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- One-day acceptance and commitment therapy (ACT) workshop improves anxiety but not vascular function or inflammation in adults with moderate to high anxiety levels in a randomized controlled trial.General hospital psychiatryTrial
- Immediate improvement in anxiety and sleep quality with delayed depression response after bariatric surgery in a longitudinal cohort study.Scientific reports · 2025Article
- Article
- [Association of body fat distribution with depression and social anxiety in children and adolescents: A cross-sectional study based on dual-energy X-ray detection].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Body Image, Social Physique Anxiety Levels and Self-Esteem among Adults Participating in Physical Activity Programs.Diseases (Basel, Switzerland) · 2023Article
- Methylation of genes and regulation of inflammatory processes on emotional response in young adults with alcoholic parents.Brain, behavior, & immunity - health · 2022Article
- Correlation between Anxiety Symptoms and Perception of Quality of Life in Women with More Than 24 Months after Undergoing Bariatric Surgery.International journal of environmental research and public health · 2022Article
- The Relationship between Empirical Dietary Inflammatory Pattern with Anthropometric Measures in Women with Overweight and Obesity: A Cross-Sectional Study.Iranian journal of public health · 2022Article
- Burden of depression and anxiety among patients with inflammatory bowel disease: results of a nationwide analysis.International journal of colorectal disease · 2022Article
- A review and novel theoretical model of how negative emotions influence inflammation: The critical role of emotion regulation.Brain, behavior, & immunity - health · 2021Article
- Prolonged saturated, but not monounsaturated, high-fat feeding provokes anxiodepressive-like behaviors in female mice despite similar metabolic consequences.Brain, behavior, & immunity - health · 2021Article
- Association between Dietary Inflammatory Index with Bioelectrical Impedance Parameters and Characteristics Health in Overweight/Obese Women: A Cross-Sectional Study.International journal of preventive medicine · 2021Article
- Depression, Anxiety, Related Risk Factors and Cognitive Distortion in Korean Patients with Inflammatory Bowel Disease.Psychiatry investigation · 2020Article
- Metabolic syndrome increases risk of venous thromboembolism recurrence after acute deep vein thrombosis.Blood advances · 2020Article
- Depression and Perceived Stress, but Not Anxiety, are Associated with Elevated Inflammation in an Obese Adult Population.Risk management and healthcare policy · 2020Article
- Article
- High serum levels of malondialdehyde and antioxidant enzymes are associated with post-stroke anxiety.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2018Observational
- Areca nut chewing is associated with common mental disorders: a population-based study.Social psychiatry and psychiatric epidemiology · 2018Article
- Suicidality in Subjects With Anxiety or Obsessive-Compulsive and Related Disorders: Recent Advances.Current psychiatry reports · 2018Review
- Inflammatory Genotype Moderates the Association Between Anxiety and Systemic Inflammation in Adults at Risk for Cardiovascular Disease.The Journal of cardiovascular nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveAnxious and depressive states are associated with increased cardiovascular disease (CVD) risk and a proinflammatory phenotype, although the latter appears to be at least partially explained by adiposity. It was hypothesized that depression and anxiety would be associated with elevated inflammation independent of adiposity in persons with obesity at high risk of CVD.
methodsThis study explored the relation between baseline anxiety as measured by the Beck Anxiety Inventory and depression as measured by the Beck Depression Inventory-II and baseline serum c-reactive protein (CRP) in a cross-sectional sample of 100 participants [mean (SD) age 57.8 (7.7) years; 64% female] with obesity [mean (SD) body mass index, BMI 37.3 (5.5) kg/m
resultsBeck Anxiety Inventory, but not Beck Depression Inventory-II, scores were significantly correlated with CRP (ρ = 0.28, P = 0.005). BMI was also highly correlated with CRP (ρ = 0.42, P < 0.0001). In multivariate models, the relation between anxiety and CRP remained significant (P = 0.038), independent of BMI, age, and sex.
conclusionsAnxiety, but not depression, was associated with elevated inflammation in persons with obesity beyond that attributable to higher BMI. Further study is warranted to assess whether anxiety represents a potential therapeutic target to mitigate corresponding CVD risk associated with elevated inflammation in persons with obesity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.