Evidence map›Paper›PMID 28000329›Full record

ArticleAngewandte Chemie (International ed. in English)2017

Polymerase-Mediated Site-Specific Incorporation of a Synthetic Fluorescent Isomorphic G Surrogate into RNA.

Yao Li, Andrea Fin, Lisa McCoy, Yitzhak Tor

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Site-specific RNA modificationRSC chemical biology · 2024
    Article
  5. Isomorphic Fluorescent Nucleosides.Accounts of chemical research · 2024
    Article
  6. Thieno[3,4-Chemical science · 2023
    Article
  7. Article
  8. Article
  9. Site-Specific Synthesis ofJournal of the American Chemical Society · 2022
    Article
  10. A New Variant of Emissive RNA Alphabets.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  11. Article
  12. Review
  13. What Makes Thienoguanosine an Outstanding Fluorescent DNA Probe?Journal of the American Chemical Society · 2020
    Article
  14. Enzymatic Syntheses and Applications of Fluorescent Cyclic Dinucleotides.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Article
  15. Article
  16. Article
  17. Emissive Synthetic Cofactors: Enzymatic Interconversions ofAngewandte Chemie (International ed. in English) · 2018
    Article
  18. A T7 RNA Polymerase Mutant Enhances the Yield of 5'-Thienoguanosine-Initiated RNAs.Chembiochem : a European journal of chemical biology · 2018
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yao LiDepartment of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0358, USA.
Andrea FinDepartment of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0358, USA.
Lisa McCoyDepartment of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0358, USA.
Yitzhak TorDepartment of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0358, USA.

Funding

Fluorescent Nucleosides and OligonucleotidesR01GM069773 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TOR, YITZHAK · 2004 to 2020
$5.0M
NIGMS NIH HHS R01 GM069773
6 · The paper itself

Abstract

An enzyme-mediated approach for the assembly of singly modified RNA constructs in which specific G residues are replaced with

Indexed as

Base SequenceDNA-Directed RNA PolymerasesFluorescent DyesGuanosineNucleic Acid ConformationRNARNA, CatalyticSubstrate SpecificityViral Proteinsbacteriophage T7 RNA polymeraseDNA-Directed RNA PolymerasesFluorescent DyesGuanosinehammerhead ribozymeRNARNA, CatalyticViral Proteinsfluorescencehammerhead ribozymenucleosidesRNAtranscription initiation

Identifiers

PMID28000329
PMCPMC5241218

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.