Evidence map›Paper›PMID 28000107›Full record

ArticleJournal of the American Society for Mass Spectrometry2017

Analytical Validation of a Portable Mass Spectrometer Featuring Interchangeable, Ambient Ionization Sources for High Throughput Forensic Evidence Screening.

Zachary E Lawton, Angelica Traub, William L Fatigante, Jose Mancias, Adam E O'Leary, Seth E Hall, Jamie R Wieland, Herbert Oberacher, Michael C Gizzi, Christopher C Mulligan

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Interpol review of controlled substances 2016-2019.Forensic science international. Synergy · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zachary E LawtonDepartment of Chemistry, Illinois State University, Normal, IL, 61790, USA.
Angelica TraubDepartment of Chemistry, Illinois State University, Normal, IL, 61790, USA.
William L FatiganteDepartment of Chemistry, Illinois State University, Normal, IL, 61790, USA.
Jose ManciasDepartment of Chemistry, Illinois State University, Normal, IL, 61790, USA.
Adam E O'LearyDepartment of Chemistry, Illinois State University, Normal, IL, 61790, USA.
Seth E HallDepartment of Chemistry, Illinois State University, Normal, IL, 61790, USA.
Jamie R WielandDepartment of Management and Quantitative Methods, Illinois State University, Normal, IL, 61790, USA.
Herbert OberacherInstitute of Legal Medicine and Core Facility Metabolomics, Innsbruck Medical University, Innsbruck, Austria.
Michael C GizziDepartment of Criminal Justice Sciences, Illinois State University, Normal, IL, 61790, USA.
Christopher C MulliganDepartment of Chemistry, Illinois State University, Normal, IL, 61790, USA. mulligan@ilstu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Forensic evidentiary backlogs are indicative of the growing need for cost-effective, high-throughput instrumental methods. One such emerging technology that shows high promise in meeting this demand while also allowing on-site forensic investigation is portable mass spectrometric (MS) instrumentation, particularly that which enables the coupling to ambient ionization techniques. While the benefits of rapid, on-site screening of contraband can be anticipated, the inherent legal implications of field-collected data necessitates that the analytical performance of technology employed be commensurate with accepted techniques. To this end, comprehensive analytical validation studies are required before broad incorporation by forensic practitioners can be considered, and are the focus of this work. Pertinent performance characteristics such as throughput, selectivity, accuracy/precision, method robustness, and ruggedness have been investigated. Reliability in the form of false positive/negative response rates is also assessed, examining the effect of variables such as user training and experience level. To provide flexibility toward broad chemical evidence analysis, a suite of rapidly-interchangeable ion sources has been developed and characterized through the analysis of common illicit chemicals and emerging threats like substituted phenethylamines. Graphical Abstract ᅟ.

Indexed as

Ambient ionizationAnalytical validationAtmospheric pressure chemical ionizationDesorption electrospray ionizationForensic evidenceForensicsPaper spray ionizationPortable mass spectrometerSWGDRUG

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.