Evidence map›Paper›PMID 27999998›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2017

p16

Diana Brauswetter, Ede Birtalan, Kornel Danos, Adrienn Kocsis, Tibor Krenacs, Jozsef Timar, Reka Mihalyi, Dorottya Horcsik, Gabor Polony, Laszlo Tamas and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Letter to the editor regarding "Surgery-based multimodal therapy outperforms chemoradiotherapy alone in HPV-negative advanced HSCC: superior outcomes for T3/N2-3 hypopharyngeal squamous cell carcinoma".European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. The correlation between FDG-PET metabolic parameters, PD-L1 expression and p16/HPV status in oropharyngeal cancers.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Prognostic nutritional index (PNI) correlates with survival in head and neck cancer patients more precisely than other nutritional markers - real world data.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  4. Article
  5. Epidemiology of HPV Related Malignancies.Seminars in radiation oncology · 2021
    Review
  6. Article
  7. Article
  8. Different patterns of p16INK4a immunohistochemical expression and their biological implications in laryngeal squamous cell carcinoma.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Diana BrauswetterMTA-SE Pathobiochemistry Research Group, Tűzoltó utca 37-47, Budapest, 1094, Hungary. brauswetter.diana@med.semmelweis-univ.hu.ORCID http://orcid.org/0000-0003-4199-282X
Ede BirtalanDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery, Semmelweis University, Szigony Str. 36, Budapest, 1083, Hungary.
Kornel DanosDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery, Semmelweis University, Szigony Str. 36, Budapest, 1083, Hungary.
Adrienn KocsisNEUMANN Diagnostics Kft., Nagyvárad Str. 15, Pécs, 7623, Hungary.
Tibor KrenacsDepartment of Pathology and Experimental Cancer Research, Semmelweis University and MTA-SE Tumorprogression Research Group, Üllői Str. 26, Budapest, 1085, Hungary.
Jozsef TimarDepartment of Pathology, Semmelweis University, Üllői Str. 93, Budapest, 1091, Hungary.
Reka MihalyiFaculty of Medicine, Semmelweis University, Üllői Str. 26, Budapest, 1085, Hungary.
Dorottya HorcsikFaculty of Medicine, Semmelweis University, Üllői Str. 26, Budapest, 1085, Hungary.
Gabor PolonyDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery, Semmelweis University, Szigony Str. 36, Budapest, 1083, Hungary.
Laszlo TamasDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery, Semmelweis University, Szigony Str. 36, Budapest, 1083, Hungary.
Istvan PetakMTA-SE Pathobiochemistry Research Group, Tűzoltó utca 37-47, Budapest, 1094, Hungary.
Semmelweis University · HUJohn von Neumann University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck cancer treatment protocols still lack well-established biomarkers of prognostic and predictive value. It is well known that human papillomavirus (HPV)-related and non-HPV-related oropharyngeal cancers are distinct entities concerning tumor biology and clinical outcome. However, there is an ongoing debate whether tumor suppressor p16

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsPapillomavirus InfectionsBiomarkers, TumorCyclin-Dependent Kinase Inhibitor p16FemaleHuman papillomavirus 16HumansHungaryImmunohistochemistryMaleMiddle AgedOropharyngeal NeoplasmsPredictive Value of TestsPrognosisBiomarkers, TumorCyclin-Dependent Kinase Inhibitor p16Head and neck cancerHPVOropharynxp16Prognosis

Identifiers

PMID27999998
OpenAlexW2564170664

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.