Evidence map›Paper›PMID 27999941›Full record

ArticlePflugers Archiv : European journal of physiology2017

Extracellular phosphates enhance activities of voltage-gated proton channels and production of reactive oxygen species in murine osteoclast-like cells.

Guangshuai Li, Katsuyuki Miura, Miyuki Kuno

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Hv1 channel in immune cells and pharmacology.Pharmacological research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Guangshuai LiDepartment of Physiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.
Katsuyuki MiuraDepartment of Applied Pharmacology and Therapeutics, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, 545-8585, Japan.
Miyuki KunoDepartment of Physiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan. kunomyk@med.osaka-cu.ac.jp.ORCID 0000-0002-7572-0446
Osaka City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoclasts are highly differentiated bone-resorbing cells and play a significant role in bone remodelling. In the resorption pit, inorganic phosphate (Pi) concentrations increase because of degradation of hydroxyapatite. We studied effects of extracellular Pi on voltage-gated H

Indexed as

AnimalsCell LineCell MembraneHydrogen-Ion ConcentrationIon Channel GatingMacrolidesMacrophagesMiceNADPH OxidasesOsteoclastsPhosphatesPhosphorylationProtein Kinase CProtonsReactive Oxygen SpeciesSodiumbafilomycin A1MacrolidesNADPH OxidasesPhosphatesProtein Kinase CProtonsReactive Oxygen SpeciesSodiumOsteoclastPhosphateProton channelReactive oxygen species

Identifiers

PMID27999941
OpenAlexW2563653268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.