Trial reportClinical research in cardiology : official journal of the German Cardiac Society2017
Impact of baseline tricuspid regurgitation on long-term clinical outcomes and survival after interventional edge-to-edge repair for mitral regurgitation.
Trial report in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 52 citations in OpenAlex.
- Concomitant transcatheter edge-to-edge treatment for mitral regurgitation and the K-Clip system for tricuspid regurgitation: one case report.Frontiers in cardiovascular medicine · 2026Article
- Validation of the COAPT risk score in Polish patients undergoing transcatheter edge-to-edge repair of severe, functional mitral regurgitation: a multicenter, observational study.Cardiology journal · 2025Observational
- Implications of Tricuspid Regurgitation Severity in Patients Undergoing Mitral Transcatheter Edge-to-Edge Repair.Journal of the American Heart Association · 2024Article
- Impact of body mass index in patients with tricuspid regurgitation after transcatheter edge-to-edge repair.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Comparison of outcomes between transcatheter tricuspid valve repair and surgical tricuspid valve replacement or repair in patients with tricuspid insufficiency.Journal of cardiothoracic surgery · 2023Article
- Mitral valve transcatheter edge-to-edge repair.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023Article
- Tricuspid valve: Once disregarded, now acknowledged.International journal of cardiology. Congenital heart disease · 2022Review
- Right ventricular function in transcatheter mitral and tricuspid valve edge-to-edge repair.Frontiers in cardiovascular medicine · 2022Review
- Predictors and prognostic relevance of tricuspid alterations in patients undergoing transcatheter edge-to-edge mitral valve repair.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021Article
- Early results of a real-world series with two transapical transcatheter mitral valve replacement devices.Clinical research in cardiology : official journal of the German Cardiac Society · 2021Article
- Mitral valve leaflet repair with the new PASCAL system: early real-world data from a German multicentre experience.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Article
- Mitral valve restenosis after closed mitral commissurotomy: case discussion.Journal of thoracic disease · 2019Article
- Invasive hemodynamics and cardiac biomarkers to predict outcomes after percutaneous edge-to-edge mitral valve repair in patients with severe heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
- Transcatheter valve interventions in heart failure: new answers to old questions.Heart failure reviews · 2018Review
- Transcatheter Tricuspid and Mitral Valve Edge-to-Edge Repair: The Double Double Orifice.CASE (Philadelphia, Pa.) · 2018Article
- Atrioventricular valve disease: challenges and achievements in percutaneous treatment.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Review
- Contemporary Trends in the Use and Outcomes of Surgical Treatment of Tricuspid Regurgitation.Journal of the American Heart Association · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTricuspid regurgitation (TR) in patients with mitral valve disease is associated with poor outcome and mortality. Only limited data on the impact of TR on functional outcome and survival in patients undergoing MitraClip procedures are available. METHODS AND
results261 patients (mean age 76.6 ± 10, EuroScore 15.9 ± 15.1%) with symptomatic mitral regurgitation (MR) (75.2% functional MR) undergoing MitraClip procedure were included and followed for 721 ± 19.4 days. At baseline 54.7% presented with TR grade 0/I, 29.5% with grade II, 13.4% with grade III and 2.3% with grade IV. When dividing groups according to baseline TR grades, follow-up (FU)-NYHA class was significantly improved only in patients with TR ≤ II (p = 0.05). FU-6-min walking distance increased significantly in the overall cohort (p = 0.05), in patients with TR ≤ II (p = 0.007), but not in patients with TR > II (p = 0.4). Moreover, FU-NT-pro-BNP levels were higher in patients with TR > II (p = 0.05), compared to patients with TR ≤ II. There was a higher mortality according to baseline TR > II and multivariate Cox regression revealed TR > II as the strongest independent predictor for mortality (hazard ratio 2.04).
conclusionsConcomitant TR at baseline negatively influences functional outcome and mortality in patients undergoing MitraClip procedures. Our results underline the need for dedicated interventional strategies for the treatment of TR in patients with symptomatic MR.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.