Evidence map›Paper›PMID 27999815›Full record

Trial reportBioMed research international2016

Assessment of the Number and Phenotype of Macrophages in the Human BMB Samples of CML.

Jian-Xin Song, Zi-Jin Dian, Yan Wen, Fen Mei, Rui-Wei Li, Ya-Lian Sa

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Targeting SHP2 phosphatase in hematological malignancies.Expert opinion on therapeutic targets · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jian-Xin SongDepartment of Clinical Laboratory, Yunnan Provincial First People's Hospital, Kunming, Yunnan 650032, China; Institute of Clinical and Basic Medical Sciences, Yunnan Provincial First People's Hospital, Kunming, Yunnan 650032, China.ORCID 0000-0002-7166-3982
Zi-Jin DianDepartment of Clinical Laboratory, Yunnan Provincial First People's Hospital, Kunming, Yunnan 650032, China.ORCID 0000-0002-4337-2520
Yan WenDepartment of Hematology, Yunnan Provincial First People's Hospital, Kunming, Yunnan 650032, China.ORCID 0000-0002-0801-9609
Fen MeiInstitute of Clinical and Basic Medical Sciences, Yunnan Provincial First People's Hospital, Kunming, Yunnan 650032, China.ORCID 0000-0003-3836-5964
Rui-Wei LiInstitute of Clinical and Basic Medical Sciences, Yunnan Provincial First People's Hospital, Kunming, Yunnan 650032, China.ORCID 0000-0002-9548-8824
Ya-Lian SaInstitute of Clinical and Basic Medical Sciences, Yunnan Provincial First People's Hospital, Kunming, Yunnan 650032, China.ORCID 0000-0002-0942-6548
First People's Hospital of Yunnan Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophages have emerged as a key player in tumor biology. However, their number and phenotype in human bone marrow of biopsy (BMB) samples of chronic myeloid leukemia (CML) and their association with disease progression from an initial chronic phase (CP) to accelerated phase (AP) to advanced blast phase (BP) are still unclear. BMB samples from 127 CML patients and 30 patients with iron-deficiency anemia (IDA) as control group were analyzed by immunohistochemistry. The expression levels of CD68, CD163, and CD206 in BMB samples of CML patients were significantly higher than those in the patients of control group (

Indexed as

Bone MarrowBone Marrow CellsGene Expression Regulation, LeukemicLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMacrophagesAdolescentAdultAgedAntigens, CDBiopsyFemaleHumansMaleMiddle AgedNeoplasm ProteinsAntigens, CDNeoplasm Proteins

Identifiers

PMID27999815
PMCPMC5143699
OpenAlexW2550811157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.