ArticleOncoimmunology
Characterization of cytokinome landscape for clinical responses in human cancers.
Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- A Signature-Based Classification of Gastric Cancer That Stratifies Tumor Immunity and Predicts Responses to PD-1 Inhibitors.Frontiers in immunology · 2021Pooled it
- A Cytokine-Related Gene Signature for Pan-Cancer Prognostic Stratification and Malignant Phenotype Characterization.International journal of molecular sciences · 2026Article
- Peripheral CaeNeuro · 2024Article
- Peripheral CabioRxiv : the preprint server for biology · 2024Article
- Prognostic and onco-immunological value of immune-related eRNAs-driven genes in lung adenocarcinoma.Journal of cancer research and clinical oncology · 2024Article
- Article
- Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 Progenitors.International journal of molecular sciences · 2021Article
- Single-cell melanoma transcriptomes depicting functional versatility and clinical implications of STIM1 in the tumor microenvironment.Theranostics · 2021Article
- Article
- Analyzing and validating the prognostic value and mechanism of colon cancer immune microenvironment.Journal of translational medicine · 2020Article
- C-C motif chemokine 14 as a novel potential biomarker for predicting the prognosis of epithelial ovarian cancer.Oncology letters · 2020Article
- Screening and Identification of Four Prognostic Genes Related to Immune Infiltration and G-Protein Coupled Receptors Pathway in Lung Adenocarcinoma.Frontiers in oncology · 2020Article
- Correlate tumor mutation burden with immune signatures in human cancers.BMC immunology · 2019Article
- Article
- Seeking for Correlative Genes and Signaling Pathways With Bone Metastasis From Breast Cancer by Integrated Analysis.Frontiers in oncology · 2019Article
- Global landscape of mouse and human cytokine transcriptional regulation.Nucleic acids research · 2018Article
- Immunogenomics Analysis Reveals that TP53 Mutations Inhibit Tumor Immunity in Gastric Cancer.Translational oncology · 2018Article
- A Comprehensive Immunologic Portrait of Triple-Negative Breast Cancer.Translational oncology · 2018Article
- Optimizing prognosis-related key miRNA-target interactions responsible for cancer metastasis.Oncotarget · 2017Article
- Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dysfunctional intratumoral immune reactions are shaped by complex networks of cytokines (including chemokines), and how the cytokinome landscape coordinates with tumors has not been systematically investigated. Using high-dimensional datasets of cancer specimens, we explored the transcript abundance, biomarker potential, and prognostic impact of local cytokines across 19 tumor types. We found that most cytokines are highly locally dysregulated (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.