Evidence map›Paper›PMID 27999665›Full record

ArticleAntimicrobial resistance and infection control2016

Estimating the morbidity and mortality associated with infections due to multidrug-resistant bacteria (MDRB), France, 2012.

M Colomb-Cotinat, J Lacoste, C Brun-Buisson, V Jarlier, B Coignard, S Vaux

Registry-linked trialAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03581370 (Comparison of Short Infusion Versus Prolonged Infusion of Ceftolozane-tazobactam Among Patients with Ventilator Associated-pneumonia to Pseudomonas Aeruginosa in Intensive Care Units), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03581370 phase3recruitingnot on this mapstarted 2018, after this paper: background citation

Comparison of Short Infusion Versus Prolonged Infusion of Ceftolozane-tazobactam Among Patients with Ventilator Associated-pneumonia to Pseudomonas Aeruginosa in Intensive Care Units

TypeinterventionalSponsorUniversity Hospital, ToulouseRan2018 to 2025Enrolled80ConditionsVentilator-associated PneumoniaArms1 hour infusion, 4 hours infusion
3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Observational
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  15. Article
  16. Genomic Characterization of ClinicalAntibiotics (Basel, Switzerland) · 2022
    Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M Colomb-CotinatSanté Publique France, The French Public Health Agency, F-94415 Saint-Maurice, France.ORCID 0000-0002-2436-3274
J LacosteSanté Publique France, The French Public Health Agency, F-94415 Saint-Maurice, France.
C Brun-BuissonAssistance publique-hôpitaux de Paris, CHU Henri Mondor, F-94000 Créteil, France.
V JarlierSorbonne Universités, UPMC Univ Paris 06, Inserm, Centre d'Immunologie et des Maladies Infectieuses, UMR 1135 & APHP, CHU Pitié-Salpêtrière, Laboratoire de Bactériologie-Hygiène, F-75013 Paris, France.
B CoignardSanté Publique France, The French Public Health Agency, F-94415 Saint-Maurice, France.
S VauxSanté Publique France, The French Public Health Agency, F-94415 Saint-Maurice, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA study based on 2007 data estimated that 386,000 infections due to multidrug-resistant bacteria (MDRB) occurred in Europe that year and 25,000 patients died from these infections. Our objective was to estimate the morbidity and mortality associated with these infections in France.

methodsThe MDRB considered were methicillin-resistant

resultsWe estimate that 158,000 (127,000 to 245,000) infections due to MDRB occurred in 2012 in France (incidence: 1.48 to 2.85 per 1000 hospital days), including 16,000 invasive infections. MRSA, 3GC-R

conclusionThese first estimates confirm that MRSA, 3GC-R

Indexed as

Antimicrobial resistanceEpidemiologyFranceInfection due to multidrug resistant bacteriaMorbidityMortality

Identifiers

PMID27999665
PMCPMC5154061

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.