Evidence map›Paper›PMID 27999574›Full record

ArticleFrontiers in immunology2016

A Previous Miscarriage and a Previous Successful Pregnancy Have a Different Impact on HLA Antibody Formation during a Subsequent Successful Pregnancy.

Kirsten Geneugelijk, Gideon Hönger, Hanneke Wilhelmina Maria van Deutekom, Irene Mathilde Hösli, Stefan Schaub, Eric Spierings

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Kirsten GeneugelijkLaboratory for Translational Immunology, University Medical Center Utrecht , Utrecht , Netherlands.
Gideon HöngerLaboratory for Transplantation Immunology and Nephrology, Department of Biomedicine, University Hospital Basel , Basel , Switzerland.
Hanneke Wilhelmina Maria van DeutekomDepartment of Theoretical Biology and Bioinformatics, University Utrecht , Utrecht , Netherlands.
Irene Mathilde HösliDepartment for Obstetrics and Fetomaternal Medicine, University Hospital Basel , Basel , Switzerland.
Stefan SchaubClinic for Transplantation Immunology and Nephrology, University Hospital Basel , Basel , Switzerland.
Eric SpieringsLaboratory for Translational Immunology, University Medical Center Utrecht , Utrecht , Netherlands.
University Hospital of Basel · CHUniversity Medical Center Utrecht · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inherited paternal HLA antigens from the semi-allogeneic fetus may trigger maternal immune responses during pregnancy, leading to the production of child-specific HLA antibodies. The prevalence of these HLA antibodies increases with the number of successful pregnancies. In the present study, we investigated the effect of a single prior miscarriage on HLA antibody formation during a subsequent successful pregnancy. Women with a successful pregnancy with one or more prior miscarriages (

Indexed as

allo-sensitizationHLA antibodiesmiscarriagePIRCHE-IIpregnancy

Identifiers

PMID27999574
PMCPMC5138233
OpenAlexW2560630506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.