Evidence map›Paper›PMID 27999573›Full record

ArticleFrontiers in microbiology2016

Reconstruction of Transcription Control Networks in Mollicutes by High-Throughput Identification of Promoters.

Gleb Y Fisunov, Irina A Garanina, Daria V Evsyutina, Tatiana A Semashko, Anastasia S Nikitina, Vadim M Govorun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  8. The Dynamics ofFrontiers in microbiology · 2021
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  12. Comparative Analysis ofFrontiers in genetics · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Gleb Y FisunovFederal Research and Clinical Centre of Physical-Chemical Medicine Moscow, Russia.
Irina A GaraninaFederal Research and Clinical Centre of Physical-Chemical MedicineMoscow, Russia; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of SciencesMoscow, Russia.
Daria V EvsyutinaFederal Research and Clinical Centre of Physical-Chemical Medicine Moscow, Russia.
Tatiana A SemashkoFederal Research and Clinical Centre of Physical-Chemical Medicine Moscow, Russia.
Anastasia S NikitinaFederal Research and Clinical Centre of Physical-Chemical MedicineMoscow, Russia; Moscow Institute of Physics and TechnologyMoscow, Russia.
Vadim M GovorunFederal Research and Clinical Centre of Physical-Chemical MedicineMoscow, Russia; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of SciencesMoscow, Russia; Moscow Institute of Physics and TechnologyMoscow, Russia.
Research Institute of Physical Chemical Medicine · RUInstitute of Bioorganic Chemistry · RUMoscow Institute of Physics and Technology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria of the class Mollicutes have significantly reduced genomes and gene expression control systems. They are also efficient pathogens that can colonize a broad range of hosts including plants and animals. Despite their simplicity, Mollicutes demonstrate complex transcriptional responses to various conditions, which contradicts their reduction in gene expression regulation mechanisms. We analyzed the conservation and distribution of transcription regulators across the 50 Mollicutes species. The majority of the transcription factors regulate transport and metabolism, and there are four transcription factors that demonstrate significant conservation across the analyzed bacteria. These factors include repressors of chaperone HrcA, cell cycle regulator MraZ and two regulators with unclear function from the WhiA and YebC/PmpR families. We then used three representative species of the major clades of Mollicutes (

Indexed as

acholeplasmaMollicutesmycoplasmapromoterspiroplasmatranscription factorstranscriptomics

Identifiers

PMID27999573
PMCPMC5138195
OpenAlexW2560210567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.