ReviewFrontiers in microbiology2016
Potential Antifungal Targets against a Candida Biofilm Based on an Enzyme in the Arachidonic Acid Cascade-A Review.
Review in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Dual-Targeting, Hybrid Antifungal Agents Targeting Candida albicans-An Overview.Chemical biology & drug design · 2026Review
- The role ofMicrobiology spectrum · 2026Article
- Exploring the anti-biofilm and gene regulatory effects of anti-inflammatory drugs on Candida albicans.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Can nonsteroidal anti-inflammatory drugs (NSAIDs) be repurposed for fungal infection?Naunyn-Schmiedeberg's archives of pharmacology · 2024Review
- In Vitro Effect of Three-Antibiotic Combinations plus Potential Antibiofilm Agents against Biofilm-ProducingAntibiotics (Basel, Switzerland) · 2023Article
- Antimicrobial Efficiency ofMicroorganisms · 2023Review
- Antimicrobial and Antibiofilm Effects of Combinatorial Treatment Formulations of Anti-Inflammatory Drugs-Common Antibiotics against Pathogenic Bacteria.Pharmaceutics · 2022Article
- Fluconazole-COX Inhibitor Hybrids: A Dual-Acting Class of Antifungal Azoles.Journal of medicinal chemistry · 2022Article
- Leaves and Fruits Preparations ofAntibiotics (Basel, Switzerland) · 2021Review
- Visible Lights Combined with Photosensitizing Compounds Are Effective against Candida albicans Biofilms.Microorganisms · 2021Article
- Mechanistic Understanding ofFrontiers in microbiology · 2021Review
- Recognition ofMicroorganisms · 2020Review
- The Pharmaceutical Ability ofAntibiotics (Basel, Switzerland) · 2020Article
- Potential targets for the development of new antifungal drugs.The Journal of antibiotics · 2018Review
- Synergistic Antifungal Effect of Fluconazole Combined with Licofelone against ResistantFrontiers in microbiology · 2017Article
- Linear Epitopes ofFrontiers in immunology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Candida is an important opportunistic fungal pathogen, especially in biofilm associated infections. The formation of a Candida biofilm can decrease Candida sensitivity to antifungal drugs and cause drug resistance. Although many effective antifungal drugs are available, their applications are limited due to their high toxicity and cost. Seeking new antifungal agents that are effective against biofilm-associated infection is an urgent need. Many research efforts are underway, and some progress has been made in this field. It has been shown that the arachidonic acid cascade plays an important role in fungal morphogenesis and pathogenicity. Notably, prostaglandin E2 (PGE
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.