Evidence map›Paper›PMID 27999534›Full record

ArticleFrontiers in human neuroscience2016

Striatal Dopaminergic Innervation Regulates Subthalamic Beta-Oscillations and Cortical-Subcortical Coupling during Movements: Preliminary Evidence in Subjects with Parkinson's Disease.

Andrea Canessa, Nicolò G Pozzi, Gabriele Arnulfo, Joachim Brumberg, Martin M Reich, Gianni Pezzoli, Maria F Ghilardi, Cordula Matthies, Frank Steigerwald, Jens Volkmann and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Parkinsonism disrupts the balance between excitatory and inhibitory activity within the primary motor cortex during movement.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  17. Direct Activation of Primary Motor Cortex during Subthalamic But Not Pallidal Deep Brain Stimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Andrea CanessaDepartment of Neurology, University Hospital and Julius-Maximilian-University Wuerzburg, Germany.
Nicolò G PozziDepartment of Neurology, University Hospital and Julius-Maximilian-University Wuerzburg, Germany.
Gabriele ArnulfoDepartment of Neurology, University Hospital and Julius-Maximilian-University Wuerzburg, Germany.
Joachim BrumbergDepartment of Nuclear Medicine, University Hospital and Julius-Maximilian-University Wuerzburg, Germany.
Martin M ReichDepartment of Neurology, University Hospital and Julius-Maximilian-University Wuerzburg, Germany.
Gianni PezzoliCentro Parkinson, ASST G. Pini-CTO Milan, Italy.
Maria F GhilardiDepartment of Physiology, Pharmacology and Neuroscience, CUNY Medical School New York, NY, USA.
Cordula MatthiesDepartment of Neurosurgery, University Hospital and Julius-Maximilian-University Wuerzburg, Germany.
Frank SteigerwaldDepartment of Neurology, University Hospital and Julius-Maximilian-University Wuerzburg, Germany.
Jens VolkmannDepartment of Neurology, University Hospital and Julius-Maximilian-University Wuerzburg, Germany.
Ioannis U IsaiasDepartment of Neurology, University Hospital and Julius-Maximilian-University Wuerzburg, Germany.
CUNY School of Law · USIstituto Ortopedico Gaetano Pini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of the basal ganglia has been shown during the preparation and execution of movement. However, the functional interaction of cortical and subcortical brain areas during movement and the relative contribution of dopaminergic striatal innervation remains unclear. We recorded local field potential (LFP) activity from the subthalamic nucleus (STN) and high-density electroencephalography (EEG) signals in four patients with Parkinson's disease (PD) off dopaminergic medication during a multi-joint motor task performed with their dominant and non-dominant hand. Recordings were performed by means of a fully-implantable deep brain stimulation (DBS) device at 4 months after surgery. Three patients also performed a single-photon computed tomography (SPECT) with [

Indexed as

beta oscillationscoherence analysisimagingmotor controlmovement disordersParkinson’s diseasesubthalamic nucleus

Identifiers

PMID27999534
PMCPMC5138226
OpenAlexW2560060708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.