Evidence map›Paper›PMID 27999532›Full record

ArticleFrontiers in neural circuits2016

Genetic Feedback Regulation of Frontal Cortical Neuronal Ensembles Through Activity-Dependent Arc Expression and Dopaminergic Input.

Surjeet Mastwal, Vania Cao, Kuan Hong Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neural circuits, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Surjeet MastwalUnit on Neural Circuits and Adaptive Behaviors, Clinical and Translational Neuroscience Branch, National Institute of Mental Health Bethesda, MD, USA.
Vania CaoUnit on Neural Circuits and Adaptive Behaviors, Clinical and Translational Neuroscience Branch, National Institute of Mental Health Bethesda, MD, USA.
Kuan Hong WangUnit on Neural Circuits and Adaptive Behaviors, Clinical and Translational Neuroscience Branch, National Institute of Mental Health Bethesda, MD, USA.
National Institute of Mental Health · US

Funding

Molecular and Cellular Mechanisms of Experience-Dependent Cortical ProcessingZIAMH002897 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI WANG, KUAN · 2009 to 2018
$12.9M
NIMH NIH HHS ZIA MH002897
6 · The paper itself

Abstract

Mental functions involve coordinated activities of specific neuronal ensembles that are embedded in complex brain circuits. Aberrant neuronal ensemble dynamics is thought to form the neurobiological basis of mental disorders. A major challenge in mental health research is to identify these cellular ensembles and determine what molecular mechanisms constrain their emergence and consolidation during development and learning. Here, we provide a perspective based on recent studies that use activity-dependent gene

Indexed as

AnimalsCytoskeletal ProteinsDopamineFeedback, PhysiologicalFrontal LobeGene Expression RegulationLearningMiceMotor ActivityNerve NetNerve Tissue Proteinsactivity regulated cytoskeletal-associated proteinCytoskeletal ProteinsDopamineNerve Tissue Proteinsactivity-dependent genetic feedbackArc/Arg3.1developmentdopaminefrontal cortical circuitslearningneuromodulationneuronal ensembles

Identifiers

PMID27999532
PMCPMC5138219
OpenAlexW2559772671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.