Evidence map›Paper›PMID 27999411›Full record

ReviewInternational journal of molecular sciences2016

Apoptosis in Cellular Society: Communication between Apoptotic Cells and Their Neighbors.

Yuhei Kawamoto, Yu-Ichiro Nakajima, Erina Kuranaga

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Animals : an open access journal from MDPI · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Ghost messages: cell death signals spread.Cell communication and signaling : CCS · 2023
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuhei KawamotoLaboratory for Histogenetic Dynamics, Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara 630-0192, Japan. ykawamoto@cdb.riken.jp.
Yu-Ichiro NakajimaLaboratory for Histogenetic Dynamics, Graduate School of Life Sciences, Tohoku University, Sendai 980-8578, Japan. yuichiro.nakajima.d2@tohoku.ac.jp.
Erina KuranagaLaboratory for Histogenetic Dynamics, Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara 630-0192, Japan. erina.kuranaga.d1@tohoku.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apoptosis is one of the cell-intrinsic suicide programs and is an essential cellular behavior for animal development and homeostasis. Traditionally, apoptosis has been regarded as a cell-autonomous phenomenon. However, recent in vivo genetic studies have revealed that apoptotic cells actively influence the behaviors of surrounding cells, including engulfment, proliferation, and production of mechanical forces. Such interactions can be bidirectional, and apoptosis is non-autonomously induced in a cellular community. Of note, it is becoming evident that active communication between apoptotic cells and living cells contributes to physiological processes during tissue remodeling, regeneration, and morphogenesis. In this review, we focus on the mutual interactions between apoptotic cells and their neighbors in cellular society and discuss issues relevant to future studies of apoptosis.

Indexed as

AnimalsApoptosisCell CommunicationCell ProliferationDrosophila melanogasterMacrophagesMorphogenesisPhagocytosisRegenerationSignal Transductionapoptosisengulfmentmechanical forcenon-cell autonomous effectsproliferation

Identifiers

PMID27999411
PMCPMC5187944

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.