Evidence map›Paper›PMID 27999393›Full record

ReviewViruses2016

Diverse Strategies Used by Picornaviruses to Escape Host RNA Decay Pathways.

Wendy Ullmer, Bert L Semler

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Pharmacological modulation of stress granulesFrontiers in pharmacology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. RNA regulatory processes in RNA virus biology.Wiley interdisciplinary reviews. RNA · 2019
    Review
  13. Review
  14. Emergency Services of Viral RNAs: Repair and Remodeling.Microbiology and molecular biology reviews : MMBR · 2018
    Review
  15. Article
  16. Article
  17. Ribonuclease fromBioMed research international · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wendy UllmerDepartment of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA 92697, USA. wullmer@uci.edu.
Bert L SemlerDepartment of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA 92697, USA. blsemler@uci.edu.
University of California, Irvine · US

Funding

Impact of host protein dynamics on picornavirus RNA 5’ noncoding region functionsR01AI026765 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI SEMLER, BERT L · 1988 to 2019
$5.9M
POLIOVIRUS GENE FUNCTION AND REGULATIONR01AI022693 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI SEMLER, BERT L · 1985 to 2015
$4.6M
Virus-host interactions: a multi-scale training programT32AI007319 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI SEMLER, BERT L, SHI, YONGSHENG · 1988 to 2024
$2.4M
Role of host cell protein TDP2 as VPg unlinkase during picornavirus replicationR01AI110782 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI SEMLER, BERT L · 2014 to 2018
$1.8M
Functions of 5' NCRs of picornavirus and cellular mRNAsR56AI026765 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI SEMLER, BERT L · 2008 to 2008
$369k
NIAID NIH HHS R01 AI022693NIAID NIH HHS R01 AI026765NIAID NIH HHS R01 AI110782NIAID NIH HHS R56 AI026765NIAID NIH HHS T32 AI007319
6 · The paper itself

Abstract

To successfully replicate, viruses protect their genomic material from degradation by the host cell. RNA viruses must contend with numerous destabilizing host cell processes including mRNA decay pathways and viral RNA (vRNA) degradation resulting from the antiviral response. Members of the

Indexed as

Host-Pathogen InteractionsImmune EvasionRNA StabilityAnimalsHumansPicornaviridaeRNA, ViralViral ProteinsRNA, ViralViral Proteinscoxsackievirusdeadenylasehuman rhinovirusmRNA decayPicornaviridaepicornaviruspoliovirusRNA degradationRNase LRNA stability

Identifiers

PMID27999393
PMCPMC5192396
OpenAlexW2561334291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.