Evidence map›Paper›PMID 27999391›Full record

ArticleViruses2016

Adenovirus with DNA Packaging Gene Mutations Increased Virus Release.

Stephen L Wechman, Xiao-Mei Rao, Kelly M McMasters, Heshan Sam Zhou

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stephen L WechmanDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40202, USA. slwech01@louisville.edu.
Xiao-Mei RaoDepartment of Surgery, University of Louisville School of Medicine, Louisville, KY 40202, USA. x0rao001@louisville.edu.
Kelly M McMastersDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40202, USA. mcmasters@louisville.edu.
Heshan Sam ZhouDepartment of Surgery, University of Louisville School of Medicine, Louisville, KY 40202, USA. hszhou01@louisville.edu.
University of Louisville · US

Funding

Adenovirus E1B55K Functions Related to Oncolytic ReplicationR01CA129975 · NCI · UNIVERSITY OF LOUISVILLE · PI ZHOU, HESHAN SAM · 2009 to 2012
$1.1M
NCI NIH HHS R01 CA129975
6 · The paper itself

Abstract

Adenoviruses (Ads) have been extensively manipulated for the development of cancer selective replication, leading to cancer cell death or oncolysis. Clinical studies using

Indexed as

DNA PackagingMutationVirus ReleaseAdenoviridaeDNA Mutational AnalysisOncolytic VirusesUltraviolet RaysViral ProteinsViral ProteinsadenovirusE1bgenomicslung cancerUV-irradiation

Identifiers

PMID27999391
PMCPMC5192394
OpenAlexW2561960515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.