Evidence map›Paper›PMID 27999380›Full record

SynthesisNutrients2016

Meta-Analysis of Milk Consumption and the Risk of Cognitive Disorders.

Lei Wu, Dali Sun

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  16. Observational
  17. Dairy products and brain structure in French older adults.The British journal of nutrition · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lei WuDepartment of Epidemiology, Institute of Geriatrics, Chinese People's Liberation Army General Hospital, Beijing 100853, China. wulei@301.cn.
Dali SunDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77096, USA. DALI.SUN@asu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between milk intake and cognitive disorders has been investigated in several epidemiological studies, but the findings are still conflicting. No quantitative assessment has been performed to evaluate the potential relationship of milk intake and cognitive disorders. From the inception to October 2016, the PubMed and the Embase databases were searched for observational studies reporting the association of milk consumption and cognitive disorders (Alzheimer's disease, dementia, and cognitive decline/impairment). A generic inverse-variance random-effects method was used to pool the Odds Ratios (ORs) and corresponding 95% confidence intervals (CIs) for the highest compared with the lowest level of milk intake. Subgroup and meta-regression analyses were used to assess the heterogeneity between subgroups. We identified seven articles involving a total of 10,941 participants. The highest level of milk consumption was significantly associated with a decreased risk of cognitive disorders, and the pooled OR (95% CI) was 0.72 (0.56, 0.93), with evidence of significant heterogeneity (

Indexed as

CognitionFeeding BehaviorMilkAdultAgedAnimalsChi-Square DistributionCognition DisordersFemaleHumansMaleMiddle AgedObservational Studies as TopicOdds RatioProtective FactorsRisk AssessmentAlzheimer’s diseasecognitive declinecognitive disordersdementiameta-analysismilk intake

Identifiers

PMID27999380
PMCPMC5188477

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.