Evidence map›Paper›PMID 27999147›Full record

ArticleJournal of lipid research2017

Quantitative profiling of endocannabinoids and related

Vasudev Kantae, Shinji Ogino, Marek Noga, Amy C Harms, Robin M van Dongen, Gerrit L J Onderwater, Arn M J M van den Maagdenberg, Gisela M Terwindt, Mario van der Stelt, Michel D Ferrari and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
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  11. Nano-liquid chromatography-mass spectrometry and recent applications in omics investigations.Analytical methods : advancing methods and applications · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Vasudev KantaeDivision of Analytical Biosciences, Leiden Academic Centre for Drug Research Leiden University, Leiden, The Netherlands.ORCID 0000-0001-8541-0882
Shinji OginoDivision of Analytical Biosciences, Leiden Academic Centre for Drug Research Leiden University, Leiden, The Netherlands.
Marek NogaDivision of Analytical Biosciences, Leiden Academic Centre for Drug Research Leiden University, Leiden, The Netherlands.
Amy C HarmsDivision of Analytical Biosciences, Leiden Academic Centre for Drug Research Leiden University, Leiden, The Netherlands.
Robin M van DongenDepartments of Neurology Leiden University Medical Center, Leiden, The Netherlands.
Gerrit L J OnderwaterDepartments of Neurology Leiden University Medical Center, Leiden, The Netherlands.
Arn M J M van den MaagdenbergDepartments of Neurology Leiden University Medical Center, Leiden, The Netherlands.
Gisela M TerwindtDepartments of Neurology Leiden University Medical Center, Leiden, The Netherlands.
Mario van der SteltDepartment of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
Michel D FerrariDepartments of Neurology Leiden University Medical Center, Leiden, The Netherlands.
Thomas HankemeierDivision of Analytical Biosciences, Leiden Academic Centre for Drug Research Leiden University, Leiden, The Netherlands hankemeier@lacdr.leidenuniv.nl.
Leiden University · NLLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocannabinoids, a class of lipid messengers, have emerged as crucial regulators of synaptic communication in the CNS. Dysregulation of these compounds has been implicated in many brain disorders. Although some studies have identified and quantified a limited number of target compounds, a method that provides comprehensive quantitative information on endocannabinoids and related

Indexed as

AdultAge FactorsArachidonic AcidsChromatography, LiquidEndocannabinoidsEthanolaminesFemaleGlyceridesHumansMaleMiddle AgedPolyunsaturated AlkamidesSex CharacteristicsTandem Mass SpectrometryanandamideArachidonic AcidsEndocannabinoidsEthanolaminesGlyceridesglyceryl 2-arachidonateN-acylethanolaminesPolyunsaturated Alkamidesbrain lipidscerebrospinal fluidlipidomicsliquid chromatographyminiaturizationquantitationtandem mass spectrometry

Identifiers

PMID27999147
PMCPMC5335577
OpenAlexW2566778288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.