Evidence map›Paper›PMID 27998976›Full record

ArticleThe Journal of biological chemistry2017

Sialylation Controls Prion Fate

Saurabh Srivastava, Elizaveta Katorcha, Martin L Daus, Peter Lasch, Michael Beekes, Ilia V Baskakov

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Sialylation in the nervous system: Functions and mechanisms.The Journal of biological chemistry · 2026
    Review
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  18. Production of Artificially Doubly Glycosylated,The Journal of organic chemistry · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Saurabh SrivastavaFrom the Center for Biomedical Engineering and Technology and.
Elizaveta KatorchaFrom the Center for Biomedical Engineering and Technology and.
Martin L Dausthe Centre for Biological Threats and Special Pathogens, Robert Koch-Institute, 13353 Berlin, Germany.
Peter Laschthe Centre for Biological Threats and Special Pathogens, Robert Koch-Institute, 13353 Berlin, Germany.
Michael Beekesthe Centre for Biological Threats and Special Pathogens, Robert Koch-Institute, 13353 Berlin, Germany.
Ilia V BaskakovFrom the Center for Biomedical Engineering and Technology and Baskakov@umaryland.edu.ORCID 0000-0003-2821-0942
Robert Koch Institute · DEUniversity of Maryland, Baltimore · US

Funding

Self-Propagating Mechanism of Prion DiseasesR01NS045585 · NINDS · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI Ilia V Baskakov · 2003 to 2026
$9.6M
NINDS NIH HHS R01 NS045585
6 · The paper itself

Abstract

Prions or PrP

Indexed as

AnimalsBlotting, WesternCricetinaeMesocricetusN-Acetylneuraminic AcidPrionsPrPSc ProteinsSpectrophotometry, InfraredN-Acetylneuraminic AcidPrionsPrPSc Proteinscyclic amplificationFourier transform IR (FTIR)N-linked glycansN-linked glycosylationprionprion diseaseprotein misfoldingsecondary lymphoid organssialic acidsialylationspleen

Identifiers

PMID27998976
PMCPMC5313106
OpenAlexW2564346784

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.