ArticleJournal of neurointerventional surgery2017
Latest generation of flat detector CT as a peri-interventional diagnostic tool: a comparative study with multidetector CT.
Article in Journal of neurointerventional surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05458908 (ProSPective Evaluation of the dIagnostic Accuracy of siNe spiN Noncontrast Flat-dEtectoR CT), which is not on this map. Cited by 29 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ProSPective Evaluation of the dIagnostic Accuracy of siNe spiN Noncontrast Flat-dEtectoR CT (FDCT) for the Detection of Intracranial Hemorrhage in Stroke Patients
Who cites it
29 citing papers in PubMed, 57 citations in OpenAlex.
- Stroke Evaluation in the Interventional Suite Using Dual-Layer Detector Cone-Beam CT: a First-in-human Prospective Cohort Study (the Next Generation X-ray Imaging System Trial).Clinical neuroradiology · 2024Trial
- Sine spin flat-detector CT for enhanced brain parenchyma visualization: an intraindividual comparison on a latest-generation angiography system.Neuroradiology · 2026Article
- One-Stop Management Improves Outcome for Large Vessel Occlusion Stroke.Stroke (Hoboken, N.J.) · 2026Article
- Size and location of intracranial hemorrhage in acute stroke presentations: correlation with baseline NIHSS and relevance to direct-to-angiography workflows.Frontiers in neurology · 2026Article
- Direct to hybrid CT-angiosuite (Nexaris) reduces treatment time for stroke thrombectomy (Direct-ST): A prospective simulation study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Article
- Utilization of flat-panel detector computed tomography for evaluation of COVID-19 pneumonia during neurointerventional procedures.Tuberkuloz ve toraks · 2024Article
- Sine Spin flat detector CT can improve cerebral soft tissue imaging: a retrospective in vivo study.European radiology experimental · 2024Article
- Review
- Extended Multimodal Flat Detector CT Imaging in Acute Ischemic Stroke: A Pilot Study.Journal of digital imaging · 2023Article
- Dual-Layer Detector Cone-Beam CT Angiography for Stroke Assessment: First-in-Human Results (the Next Generation X-ray Imaging System Trial).AJNR. American journal of neuroradiology · 2023Article
- Can flat-detector CT after successful endovascular treatment predict long-term outcome in patients with large vessel occlusion? An Alberta Stroke Programme Early CT Score-based study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Review
- Evaluation of Sine Spin flat detector CT imaging compared with multidetector CT.Journal of neurointerventional surgery · 2023Article
- The butterfly effect: improving brain cone-beam CT image artifacts for stroke assessment using a novel dual-axis trajectory.Journal of neurointerventional surgery · 2023Article
- Clinical Comparison of FD-CT and MS-CT in Aneurysmal Subarachnoid Haemorrhage: A Single Center Experience.Diagnostics (Basel, Switzerland) · 2022Article
- Flat Detector CT with Cerebral Pooled Blood Volume Perfusion in the Angiography Suite: From Diagnostics to Treatment Monitoring.Diagnostics (Basel, Switzerland) · 2022Review
- Direct transfer of acute stroke patients to angiography suites equipped with flat-detector computed tomography: literature review and initial single-centre experience.European heart journal supplements : journal of the European Society of Cardiology · 2022Article
- Direct to angiography suite approaches for the triage of suspected acute stroke patients: a systematic review and meta-analysis.Therapeutic advances in neurological disorders · 2022Article
- Major complications of dural venous sinus stenting for idiopathic intracranial hypertension: case series and management considerations.Journal of neurointerventional surgery · 2022Article
- Effective dose to patient measurements for flat-detector computed tomography protocols in acute stroke care.European radiology · 2020Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeFlat detector CT (FDCT) has been used as a peri-interventional diagnostic tool in numerous studies with mixed results regarding image quality and detection of intracranial lesions. We compared the diagnostic aspects of the latest generation FDCT with standard multidetector CT (MDCT). MATERIALS AND
methods102 patients were included in our retrospective study. All patients had undergone interventional procedures. FDCT was acquired peri-interventionally and compared with postinterventional MDCT regarding depiction of ventricular/subarachnoidal spaces, detection of intracranial hemorrhage, and delineation of ischemic lesions using an ordinal scale. Ischemic lesions were quantified with the Alberta Stroke Program Early CT Scale (ASPECTS) on both examinations. Two neuroradiologists with varying grades of experience and a medical student scored the anonymized images separately, blinded to the clinical history.
resultsThe two methods were of equal diagnostic value regarding evaluation of the ventricular system and the subarachnoidal spaces. Subarachnoidal, intraventricular, and parenchymal hemorrhages were detected with a sensitivity of 95%, 97%, and 100% and specificity of 97%, 100%, and 99%, respectively, using FDCT. Gray-white differentiation was feasible in the majority of FDCT scans, and ischemic lesions were detected with a sensitivity of 71% on FDCT, compared with MDCT scans. The mean difference in ASPECTS values on FDCT and MDCT was 0.5 points (95% CI 0.12 to 0.88).
conclusionsThe latest generation of FDCT is a reliable and accurate tool for the detection of intracranial hemorrhage. Gray-white differentiation is feasible in the supratentorial region.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.