Evidence map›Paper›PMID 27998778›Full record

ArticleNeuroscience2017

Polyunsaturated fatty acid biostatus, phospholipase A

Robert K McNamara, Philip R Szeszko, Stefan Smesny, Toshikazu Ikuta, Pamela DeRosse, Frédéric M Vaz, Berko Milleit, Uta-Christina Hipler, Cornelia Wiegand, Jana Hesse and 3 more

Abstract read
In one paragraph

Article in Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Robert K McNamaraDepartment of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA. Electronic address: mcnamar@ucmail.uc.edu.
Philip R SzeszkoDivision of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address: philip.szeszko@mssm.edu.
Stefan SmesnyDepartment of Psychiatry, University Hospital Jena, D-07743 Jena, Germany. Electronic address: stefan.smesny@med.uni-jena.de.
Toshikazu IkutaDivision of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address: tikuta@umail.iu.edu.
Pamela DeRosseDivision of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address: pderosse@NSHS.edu.
Frédéric M VazLaboratory Genetic Metabolic Diseases, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands. Electronic address: f.m.vaz@amc.uva.nl.
Berko MilleitDepartment of Dermatology, University Hospital Jena, Erfurter Straße 35, D-07743 Jena, Germany. Electronic address: berko.milleit@med.uni-jena.de.
Uta-Christina HiplerDepartment of Dermatology, University Hospital Jena, Erfurter Straße 35, D-07743 Jena, Germany. Electronic address: christina.hipler@med.uni-jena.de.
Cornelia WiegandDepartment of Dermatology, University Hospital Jena, Erfurter Straße 35, D-07743 Jena, Germany. Electronic address: C.Wiegand@med.uni-jena.de.
Jana HesseDepartment of Dermatology, University Hospital Jena, Erfurter Straße 35, D-07743 Jena, Germany. Electronic address: jana.hesse@med.uni-jena.de.
G Paul AmmingerOrygen, the National Centre of Excellence in Youth Mental Health, Parkville, Australia; Centre for Youth Mental Health, The University of Melbourne, Parkville VIC 3052, Australia. Electronic address: amminger@unimelb.edu.au.
Anil K MalhotraDivision of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address: amalhotra@nshs.edu.
Bart D PetersDivision of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address: petersbart@hotmail.com.
Jena University Hospital · DEZucker Hillside Hospital · USAcademic Medical Center · NLFeinstein Institute for Medical Research · USOrygen Youth Health · AUUniversity of Cincinnati Medical Center · US

Funding

WHITE MATTER STRUCTURAL DEFICITS IN HIGH FUNCTIONING CHILDREN WITH AUTISM SPEM01RR018535 · NCRR · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI SCHWARTZ, GUY · 2003 to 2010
$19.5M
Striatal D2/D3 Dopamine receptor availability in first episode schizophreniaP50MH080173 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI GREGERSEN, PETER K. · 2008 to 2012
$10.4M
Trials Operation Unit (OPERATIONS CORE)P30MH090590 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI CORRELL, CHRISTOPH U · 2010 to 2014
$7.9M
Risk and protective factors for SGA-induced metabolic syndrome in bipolar youthR01DK097599 · NIDDK · UNIVERSITY OF CINCINNATI · PI MCNAMARA, ROBERT K. · 2013 to 2017
$1.7M
Diffusion Tensor Imaging in First-Episode SchizophreniaR01MH076995 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI SZESZKO, PHILIP R · 2007 to 2010
$1.2M
NCRR NIH HHS M01 RR018535NIDDK NIH HHS R01 DK097599NIMH NIH HHS P30 MH090590NIMH NIH HHS P50 MH080173NIMH NIH HHS R01 MH076995
6 · The paper itself

Abstract

Adolescence is a period of major brain white matter (WM) changes, and membrane lipid metabolism likely plays a critical role in brain WM myelination. Long-chain polyunsaturated fatty acids (LC-PUFAs) are essential components of cell membranes including oligodendrocytes, and LC-PUFA release and turnover in membranes is regulated by phospholipase A

Indexed as

AdolescentBrainChildDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingDocosahexaenoic AcidsEicosapentaenoic AcidErythrocytesFemaleHumansMaleMyelin SheathPhospholipases A2Sex FactorsWhite MatterYoung AdultDocosahexaenoic AcidsEicosapentaenoic AcidPhospholipases A2adolescencedevelopmentmyelinphospholipasepolyunsaturated fatty acidswhite matter

Identifiers

PMID27998778
PMCPMC6029616
OpenAlexW2562298215

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.