ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2016
Gastrojejunal anastomotic reduction for weight regain in roux-en-y gastric bypass patients: physiological, behavioral, and anatomical effects of endoscopic suturing and sclerotherapy.
Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- The use of endoluminal techniques in the revision of primary bariatric surgery procedures: a systematic review.Surgical endoscopy · 2020Pooled it
- Transoral outlet reduction with full thickness endoscopic suturing for weight regain after gastric bypass: a large multicenter international experience and meta-analysis.Surgical endoscopy · 2018Pooled it
- Endoscopic Treatment of Weight Regain Following Roux-en-Y Gastric Bypass: a Systematic Review and Meta-analysis.Obesity surgery · 2018Pooled it
- Prognosticating post-bariatric surgery outcomes and management of postoperative recurrent weight gain and diabetes recurrence.Frontiers in nutrition · 2024Review
- A Comprehensive Review on Bariatric Endoscopy: Where We Are Now and Where We Are Going.Medicina (Kaunas, Lithuania) · 2023Review
- Bariatric endoscopy: from managing complications to primary metabolic procedures.Journal of minimally invasive surgery · 2023Review
- Insufficient weight loss after banded vs. non-banded primary gastric bypass surgery: insights from an observational 5 year follow-up study.Surgical endoscopy · 2022Observational
- Endoscopic Management of Weight Recurrence Following Bariatric Surgery.Frontiers in endocrinology · 2022Review
- Endoscopic therapy of weight regain after bariatric surgery.World journal of gastrointestinal surgery · 2021Review
- Examination of the Eating Behavior of the Hungarian Population Based on the TFEQ-R21 Model.Nutrients · 2020Article
- Efficacy of transoral outlet reduction in Roux-en-Y gastric bypass patients to promote weight loss: a systematic review and meta-analysis.Endoscopy international open · 2020Article
- A Real-World, Insurance-Based Algorithm Using the Two-Fold Running Suture Technique for Transoral Outlet Reduction for Weight Regain and Dumping Syndrome After Roux-En-Y Gastric Bypass.Obesity surgery · 2019Article
- Endoscopic gastrojejunostomy revision is more effective than medical management alone to address weight regain after RYGB.Surgical endoscopy · 2018Article
- Development of Bariatric and Metabolic Endoscopy.Chinese medical journal · 2018Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundWeight regain is common after Roux-en-Y gastric bypass.
objectivesTo assess the mechanisms of weight loss after 2 gastrojejunal anastomotic reduction (GJAR) procedures to treat weight regain.
settingUniversity hospital, United States.
methodsForty-three Roux-en-Y gastric bypass patients with weight regain were prospectively enrolled. Weight, ghrelin levels, responses to the 21-item three-factor eating questionnaire, and gastrojejunal anastomotic diameter were assessed. Nine patients underwent endoscopic suturing and 34 patients underwent sclerotherapy. At 3 months, weight, ghrelin levels, eating behavior, and outlet diameter were reassessed.
resultsPatients were aged 47±10 years and regained 43%±26% of maximal lost weight. Ghrelin levels were 123±106 ng/mL and outlet diameter was 21±6.3 mm. At 3 months, the entire cohort lost 4.1%±5.9% of total weight (TBW) and showed improvement in cognitive eating habits (P<.01). Endoscopic suturing and sclerotherapy patients lost 10.4%±2.2% TBW and 2.7%±5.5% TBW (P<.01), respectively. Suturing and sclerotherapy reduced the outlet diameter by 15.0±6.7 mm and 2.6±5.7 mm (P<.01). Ghrelin levels increased after suturing by 46±55 ng/mL and decreased by 37±110 ng/mL after sclerotherapy (P = .02). Suturing resulted in greater improvement in cognitive eating behavior than sclerotherapy (P = .03). Reduction in outlet size and changes in cognitive and emotional eating behaviors were predictors of weight loss after GJAR on a univariate analysis. On a multivariate analysis, the only predictor of weight loss was a reduction in outlet size (P< .01).
conclusionsEndoscopic suturing resulted in greater reduction in outlet size, improvement in eating behavior, and weight loss than sclerotherapy. Reduction of anastomosis size was a significant predictor of weight loss after GJAR.
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