ArticleMicrobiome2016
Resilient microorganisms in dust samples of the International Space Station-survival of the adaptation specialists.
Article in Microbiome, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 77 citations in OpenAlex.
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- Bacterial resistance across habitats: from German schools to the International Space Station.Frontiers in microbiology · 2026Article
- Community matters: stress tolerance and survival ofFrontiers in microbiology · 2026Article
- Touching Surfaces - Presence of microorganisms on antimicrobial metal surfaces on the International Space Station and in German schools.BMC microbiology · 2025Article
- The evolution of superbugs in space: a genomic perspective on pathogens in the International Space Station environment.Journal, genetic engineering & biotechnology · 2025Article
- Extremophiles and Extremophilic Behaviour-New Insights and Perspectives.Life (Basel, Switzerland) · 2024Review
- Microbiome in a ground-based analog cabin of China Space Station during a 50-day human occupation.ISME communications · 2024Article
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- Microbial Detection and Quantification of Low-Biomass Water Samples Using an International Space Station Smart Sample Concentrator.Microorganisms · 2023Article
- Metagenome Analysis Reveals a Response of the Antibiotic Resistome to Mars-like Extraterrestrial Conditions.Astrobiology · 2022Article
- Phenotypic, genomic, and transcriptomic changes in an Acinetobacter baumannii strain after spaceflight in China's Tiangong-2 space laboratory.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station.Microbiome · 2022Article
- Hospital sink traps as a potential source of the emerging multidrug-resistant pathogenJournal of medical microbiology · 2022Article
- The Isolation and Characterization of Rare Mycobiome Associated With Spacecraft Assembly Cleanrooms.Frontiers in microbiology · 2022Article
- Advances in space microbiology.iScience · 2021Review
- Taxonomic and functional analyses of intact microbial communities thriving in extreme, astrobiology-relevant, anoxic sites.Microbiome · 2021Article
- Microbiome dynamics during the HI-SEAS IV mission, and implications for future crewed missions beyond Earth.Microbiome · 2021Article
- Review
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe International Space Station (ISS) represents a unique biotope for the human crew but also for introduced microorganisms. Microbes experience selective pressures such as microgravity, desiccation, poor nutrient-availability due to cleaning, and an increased radiation level. We hypothesized that the microbial community inside the ISS is modified by adapting to these stresses. For this reason, we analyzed 8-12 years old dust samples from Russian ISS modules with major focus on the long-time surviving portion of the microbial community. We consequently assessed the cultivable microbiota of these samples in order to analyze their extremotolerant potential against desiccation, heat-shock, and clinically relevant antibiotics. In addition, we studied the bacterial and archaeal communities from the stored Russian dust samples via molecular methods (next-generation sequencing, NGS) and compared our new data with previously derived information from the US American ISS dust microbiome.
resultsWe cultivated and identified in total 85 bacterial, non-pathogenic isolates (17 different species) and 1 fungal isolate from the 8-12 year old dust samples collected in the Russian segment of the ISS. Most of these isolates exhibited robust resistance against heat-shock and clinically relevant antibiotics. Microbial 16S rRNA gene and archaeal 16S rRNA gene targeting Next Generation Sequencing showed signatures of human-associated microorganisms (Corynebacterium, Staphylococcus, Coprococcus etc.), but also specifically adapted extremotolerant microorganisms. Besides bacteria, the detection of archaeal signatures in higher abundance was striking.
conclusionsOur findings reveal (i) the occurrence of living, hardy microorganisms in archived Russian ISS dust samples, (ii) a profound resistance capacity of ISS microorganisms against environmental stresses, and (iii) the presence of archaeal signatures on board. In addition, we found indications that the microbial community in the Russian segment dust samples was different to recently reported US American ISS microbiota.
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