Evidence map›Paper›PMID 27998301›Full record

ReviewJournal of medical case reports2016

Acute polyarthritis in a young patient caused by meningococcal and parvovirus B19 infections: a case report and review of the literature.

Virginie Lavoipierre, Anna Dellyes, Camille Aubry, Christine Zandotti, Pierre Lafforgue, Philippe Parola, Jean-Christophe Lagier

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Journal of medical case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Virginie LavoipierreService de Maladies Infectieuses Aigues, Pôle Maladies Infectieuses, Assistance Publique Hôpitaux de Marseille, CHU Timone, Institut Hospitalo-Universitaire Méditerranée Infection, 13005, Marseille, France.
Anna DellyesService de Rhumatologie, Assistance Publique Hôpitaux de Marseille, CHU Sainte Marguerite, 13009, Marseille, France.
Camille AubryService de Maladies Infectieuses Aigues, Pôle Maladies Infectieuses, Assistance Publique Hôpitaux de Marseille, CHU Timone, Institut Hospitalo-Universitaire Méditerranée Infection, 13005, Marseille, France.
Christine ZandottiPôle Maladies Infectieuses, Fédération de Microbiologie, Assistance Publique Hôpitaux de Marseille, CHU Timone, Institut Hospitalo-Universitaire Méditerranée Infection, 13015, Marseille, France.
Pierre LafforgueService de Rhumatologie, Assistance Publique Hôpitaux de Marseille, CHU Sainte Marguerite, 13009, Marseille, France.
Philippe ParolaService de Maladies Infectieuses Aigues, Pôle Maladies Infectieuses, Assistance Publique Hôpitaux de Marseille, CHU Timone, Institut Hospitalo-Universitaire Méditerranée Infection, 13005, Marseille, France.
Jean-Christophe LagierService de Maladies Infectieuses Aigues, Pôle Maladies Infectieuses, Assistance Publique Hôpitaux de Marseille, CHU Timone, Institut Hospitalo-Universitaire Méditerranée Infection, 13005, Marseille, France. jean-christophe.lagier@ap-hm.fr.
Assistance Publique Hôpitaux de Marseille · FRHôpital Sainte-Marguerite · FRCentre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMeningococcal infection is a multifaceted disease including acute polyarthritis. This presentation should be known by clinicians in order to prevent delay in treatment. We report what we believe to be the first case of an association of parvovirus B19 and meningococcal polyarthritis in a young adult. CASE PRESENTATION: A 19-year-old Caucasian woman presented to our hospital with fever, intense leg pain, and a transient rash. A physical examination showed asymmetric polyarthritis and no neurological abnormalities. A parvovirus B19 polymerase chain reaction performed using a blood sample and knee fluid aspirate came back positive, but serology was negative for immunoglobulin M and positive for immunoglobulin G. A blood culture was positive for serotype C meningococcus; a polymerase chain reaction performed for Neisseria meningitidis was positive in joint fluid but negative in blood samples (performed after antibiotic treatment had begun). Our patient was treated with ceftriaxone for 15 days, associated with analgesic therapy. Hydroxychloroquine treatment was introduced 5 months after the onset of polyarthritis because of persisting inflammatory arthralgia.

conclusionsTo the best of our knowledge, this is the first case report of polyarthritis caused by concomitant meningococcal and parvovirus B19 infections. This unusual presentation of meningococcal disease may have resulted from the persistent parvovirus B19 infection. Our experience with this case illustrates the need for a systematic approach to the diagnosis of febrile acute polyarthritis. Only long-term follow-up will reveal if this infectious polyarthritis will evolve towards an autoimmune rheumatism.

Indexed as

AnalgesiaAnti-Bacterial AgentsAntibodies, ViralArthritisCeftriaxoneDrug Therapy, CombinationFemaleHumansMeningococcal InfectionsPainPain MeasurementParvoviridae InfectionsParvovirus B19, HumanPhlebitisPolymerase Chain ReactionTreatment OutcomeAnti-Bacterial AgentsAntibodies, ViralCeftriaxoneCase reportMeningococcemiaParvovirus B19Polyarthritis

Identifiers

PMID27998301
PMCPMC5175313
OpenAlexW2564928057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.