ArticleJournal of endourology2017
Ureteral Access Sheath Influence on the Ureteral Wall Evaluated by Cyclooxygenase-2 and Tumor Necrosis Factor-α in a Porcine Model.
Article in Journal of endourology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Use of the ureteral access sheath during ureteroscopy: A systematic review and meta-analysis.PloS one · 2018Pooled it
- Iatrogenic upper urinary tract injuries during ureteroscopy for urolithiasis: a comprehensive review on incidence, mechanisms and preventative strategies.Nature reviews. Urology · 2025Review
- Effective ureteral access sheath insertion during flexible ureteroscopy: Influence of the ureteral orifice configuration.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022Article
- Article
- Predictors of emergency department attendance following ureterorenoscopy for urolithiasis.Irish journal of medical science · 2020Article
- Controversies associated with ureteral access sheath placement during ureteroscopy.Investigative and clinical urology · 2020Review
- Impact of previous SWL on ureterorenoscopy outcomes and optimal timing for ureterorenoscopy after SWL failure in proximal ureteral stones.World journal of urology · 2020Article
- Practice patterns of ureteral access sheath during ureteroscopy for nephrolithiasis: a survey among endourologists worldwide.BMC urology · 2019Article
- Risks of flexible ureterorenoscopy: pathophysiology and prevention.Urolithiasis · 2018Review
- Histopathological correlations to ureteral lesions visualized during ureteroscopy.World journal of urology · 2017Article
- Review
- Failure of ureteral access sheath insertion in virgin ureters: A retrospective tertiary care center study.Urology annalsArticle
- Ureteral access sheath. Does it improve the results of flexible ureteroscopy? A narrative review.International braz j urol : official journal of the Brazilian Society of UrologyArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the effect of ureteral access sheath (UAS) on the expression of the pro-inflammatory mediators cyclooxygenase-2 (COX-2) and tumor necrosis factor-α (TNF-α) in the ureteral wall. MATERIAL AND
methodsIn 22 pigs an UAS was inserted and removed after 2 minutes on one side and 2 hours on the contralateral side. Postoperatively ureters were excised in vivo, and tissue samples from the distal (2 minutes/2 hours) and proximal ureter (2 minutes/2 hours) were snap-frozen before quantitative polymerase chain reaction analysis of COX-2 and TNF-α. Five unmanipulated ureteral units from other pigs served as the control group.
resultsCompared to controls COX-2 mRNA was significantly upregulated in all UAS treated ureteral groups. Similarly, TNF-α mRNA was upregulated in all groups except the 2-minute proximal ureteral group. Both COX-2 and TNF-α expression were significantly higher in the distal than in the proximal ureter in the UAS treated ureters. After UAS insertion for 2 minutes, expression levels in the distal ureter were increased 6.5- and 8-fold for COX-2 and TNF-α, respectively; and after 2 hours of UAS placement COX-2 and TNF-α mRNA expression levels were increased 9- and 9.5-fold, respectively.
conclusionThe pro-inflammatory mediators COX-2 and TNF-α were significantly upregulated in the ureteral wall by the influence of UAS. These findings may have implications for postoperative pain, drainage, and complications.
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Registered trials
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