Evidence map›Paper›PMID 27998171›Full record

ArticleAIDS care2017

Co-infections of tuberculosis, hepatitis B or C viruses in a cohort of people living with HIV/AIDS in China: predictors and sequelae.

Chen Zhang, Xiaoming Li, Yu Liu, Shan Qiao, Yi Chen, Yuejiao Zhou, Zhiyong Shen

Abstract read
In one paragraph

Article in AIDS care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Hepatotoxicity and tuberculosis treatment outcomes in chronic liver disease.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2023
    Article
  12. Tuberculosis among Ambulatory People Living with HIV in Guangxi Province, China: A Longitudinal Study.International journal of environmental research and public health · 2022
    Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chen Zhanga Vanderbilt Institute for Global Health , Vanderbilt University School of Medicine , Nashville , TN , USA.ORCID 0000-0002-8771-561X
Xiaoming Lib Arnold School of Public Health , University of South Carolina , Columbia , SC , USA.
Yu Liua Vanderbilt Institute for Global Health , Vanderbilt University School of Medicine , Nashville , TN , USA.
Shan Qiaob Arnold School of Public Health , University of South Carolina , Columbia , SC , USA.
Yi Chenc Division of HIV/STD Prevention, Guangxi Center for Disease Control and Prevention , Nanning , People's Republic of China.
Yuejiao Zhouc Division of HIV/STD Prevention, Guangxi Center for Disease Control and Prevention , Nanning , People's Republic of China.
Zhiyong Shenc Division of HIV/STD Prevention, Guangxi Center for Disease Control and Prevention , Nanning , People's Republic of China.

Funding

Venue-based HIV and alcohol use risk reduction among female sex workers in ChinaR01AA018090 · NIAAA · WAYNE STATE UNIVERSITY · PI LI, XIAOMING · 2008 to 2012
$2.6M
Theory-based HIV Disclosure Intervention for ParentsR01HD074221 · NICHD · WAYNE STATE UNIVERSITY · PI LI, XIAOMING · 2012 to 2017
$1.7M
NIAAA NIH HHS R01 AA018090NICHD NIH HHS R01 HD074221
6 · The paper itself

Abstract

The co-infection of viral hepatitis and tuberculosis (TB) among people living with HIV/AIDS (PLWHA) makes the syndemic of HIV even worse as there is higher mortality and morbidity among PLWHA with co-infections compared to people with HIV mono-infection. In the current study, we explored predictors and sequelae among a group of Chinese PLWHA to guide future program strategies and enhance the repertoire of action for both preventative and clinical purposes. Between October 2012 and August 2013, we conducted a cross-sectional study in Guangxi Autonomous Region (Guangxi) of China. With an overall participation rate of 90%, we finally recruited 3002 patients with 2987 (99.5%) completed the survey and were included in the data analysis. We employed both predictive and explanatory modeling strategies to explore predictors and sequelae of co-infections among PLWHA. The overall prevalence of co-infection was 15.6% with 4.4% of HBV, 5.4% of HCV and 4.8% of TB, respectively. Predictors of co-infections included history of injecting drugs or drinking alcohol, sharing needles, having sex with sex workers or casual partners, higher viral loads and lower CD4 counts. Meanwhile, co-infections were associated with various physical and psychological problems among PLWHA. As an entangled phenomenon, co-infections among PLWHA produce continuous and shifting scenarios, which add complexity to clinic, epidemiological and political ways of dealing with health risks among PLWHA in China. Exploring predictors and sequelae can help to prevent and manage co-infection comorbidities among PLWHA.

Indexed as

AdultChinaCohort StudiesCoinfectionCross-Sectional StudiesFemaleHepatitis BHepatitis CHIV InfectionsHumansMaleMiddle AgedPrevalenceSexual PartnersTuberculosisYoung AdultChinaco-infectionsHBVHCVPeople living with HIV/AIDSTB

Identifiers

PMID27998171
PMCPMC8170663

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.