Evidence map›Paper›PMID 27998058›Full record

ArticleJournal of proteome research2017

Label-Free Neuroproteomics of the Hippocampal-Accumbal Circuit Reveals Deficits in Neurotransmitter and Neuropeptide Signaling in Mice Lacking Ethanol-Sensitive Adenosine Transporter.

Alfredo Oliveros, Phillip Starski, Daniel Lindberg, Sun Choi, Carrie J Heppelmann, Surendra Dasari, Doo-Sup Choi

Open access · greenAbstract read
In one paragraph

Article in Journal of proteome research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Who Is Who in Adenosine Transport.Frontiers in pharmacology · 2018
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alfredo OliverosDepartment of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic , Rochester, Minnesota 55905, United States.
Phillip StarskiNeurobiology of Disease Program, Mayo Clinic , Rochester, Minnesota 55905, United States.
Daniel LindbergNeurobiology of Disease Program, Mayo Clinic , Rochester, Minnesota 55905, United States.
Sun ChoiDepartment of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic , Rochester, Minnesota 55905, United States.
Carrie J HeppelmannProteomics Research Center, Mayo Clinic , Rochester, Minnesota 55905, United States.
Surendra DasariDivision of Biomedical Statistics and Informatics, Mayo Clinic , Rochester, Minnesota 55905, United States.
Doo-Sup ChoiDepartment of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic , Rochester, Minnesota 55905, United States.ORCID 0000-0002-6796-9938
Mayo Clinic · US

Funding

TRAINING IN TRANSLATIONAL RESEARCH: BENCH TO BEDSIDER25GM055252 · NIGMS · MAYO CLINIC ROCHESTER · PI LUJAN, LUIS, MAHER, LOUIS JAMES · 1996 to 2022
$8.3M
Alcohol and Adenosine-Mediated Glutamate Signaling in Neuro-Glial InteractionR01AA018779 · NIAAA · MAYO CLINIC ROCHESTER · PI CHOI, DOO-SUP · 2009 to 2019
$3.8M
NIAAA NIH HHS R01 AA018779NIGMS NIH HHS R25 GM055252
6 · The paper itself

Abstract

The neural circuit of the dorsal hippocampus (dHip) and nucleus accumbens (NAc) contributes to cue-induced learning and addictive behaviors, as demonstrated by the escalation of ethanol-seeking behaviors observed following deletion of the adenosine equilibrative nucleoside transporter 1 (ENT1

Indexed as

ProteomicsAlcohol DrinkingAnimalsEnkephalinsEquilibrative Nucleoside Transporter 1EthanolHippocampusLong-Term PotentiationMiceNeuropeptidesNeurotransmitter AgentsNucleus AccumbensProprotein Convertase 1Protein PrecursorsSignal TransductionTandem Mass SpectrometryEnkephalinsEquilibrative Nucleoside Transporter 1EthanolNeuropeptidesNeurotransmitter AgentsPcsk1 protein, mousepreproenkephalinProprotein Convertase 1Protein PrecursorsSLC29A1 protein, mouseVesicle-Associated Membrane Protein 1vesicle-associated membrane protein 1, mouseadenosineENT1hippocampusneuroproteomicsnucleus accumbens

Identifiers

PMID27998058
PMCPMC5384880
OpenAlexW2562035692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.