Evidence map›Paper›PMID 27997763›Full record

ArticleJournal of cellular and molecular medicine2017

The stem cell growth factor receptor KIT is not expressed on interstitial cells in bladder.

Thomas Gevaert, Dirk De Ridder, Els Vanstreels, Dirk Daelemans, Wouter Everaerts, Frank Van Der Aa, Isabel Pintelon, Jean-Pierre Timmermans, Tania Roskams, Clara Steiner and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Defining the molecular fingerprint of bladder and kidney fibroblasts.American journal of physiology. Renal physiology · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Thomas GevaertLaboratory of Experimental Urology, Organ Systems, KU Leuven, Leuven, Belgium.
Dirk De RidderLaboratory of Experimental Urology, Organ Systems, KU Leuven, Leuven, Belgium.
Els VanstreelsRega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Dirk DaelemansRega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Wouter EveraertsLaboratory of Experimental Urology, Organ Systems, KU Leuven, Leuven, Belgium.
Frank Van Der AaLaboratory of Experimental Urology, Organ Systems, KU Leuven, Leuven, Belgium.
Isabel PintelonDepartment of Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
Jean-Pierre TimmermansDepartment of Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
Tania RoskamsTranslational Cell and Tissue Research, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Clara SteinerKlinik und Poliklinik für Urologie, University of Leipzig, Leipzig, Germany.
Jochen NeuhausKlinik und Poliklinik für Urologie, University of Leipzig, Leipzig, Germany.
KU Leuven · BEKlinik und Poliklinik für Urologie · DERega Institute for Medical Research · BEUniversity of Antwerp · BEOrgan Recovery Systems (Belgium) · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mast/stem cell growth factor receptor KIT has long been assumed to be a specific marker for interstitial cells of Cajal (ICC) in the bladder, with possible druggable perspectives. However, several authors have challenged the presence of KIT

Indexed as

AnimalsGene Expression RegulationGuinea PigsHumansInterstitial Cells of CajalMast CellsMiceMuscle, SmoothProto-Oncogene Proteins c-kitRatsStem CellsUrinary BladderProto-Oncogene Proteins c-kitbladderimmunofluorescenceimmunohistochemistryinterstitial cellsKITmast cells

Identifiers

PMID27997763
PMCPMC5431123
OpenAlexW2564545225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.