ArticleEmerging infectious diseases2017
Detection of Multiple Parallel Transmission Outbreak of Streptococcus suis Human Infection by Use of Genome Epidemiology, China, 2005.
Article in Emerging infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Identification ofVirulence · 2021Pooled it
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- A rapid colloidal gold immunochromatographic assay based on polyclonal antibodies against HtpsC protein for the detection ofFrontiers in microbiology · 2023Article
- Acquiring high expression of suilysin enable non-epidemicEmerging microbes & infections · 2021Article
- The global emergence of a novel Streptococcus suis clade associated with human infections.EMBO molecular medicine · 2021Article
- Proposed virulence-associated genes of Streptococcus suis isolates from the United States serve as predictors of pathogenicity.Porcine health management · 2021Article
- Tools for Molecular Epidemiology ofPathogens (Basel, Switzerland) · 2020Review
- Genomic Epidemiology of an Outbreak ofInfection and drug resistance · 2020Article
- Genomic Epidemiology ofPathogens (Basel, Switzerland) · 2019Article
- Whole-Genome Sequencing Reveals a Prolonged and Persistent Intrahospital Transmission of Corynebacterium striatum, an Emerging Multidrug-Resistant Pathogen.Journal of clinical microbiology · 2019Article
- Reinfection with Streptococcus suis analysed by whole genome sequencing.Zoonoses and public health · 2019Article
- Transforming bacterial disease surveillance and investigation using whole-genome sequence to probe the trace.Frontiers of medicine · 2018Review
- Landscape of emerging and re-emerging infectious diseases in China: impact of ecology, climate, and behavior.Frontiers of medicine · 2018Review
- Genomic comparisons of Streptococcus suis serotype 9 strains recovered from diseased pigs in Spain and Canada.Veterinary research · 2018Article
- Whole genome sequence revealed the fine transmission map of carbapenem-resistantAntimicrobial resistance and infection control · 2018Article
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Streptococcus suis sequence type 7 emerged and caused 2 of the largest human infection outbreaks in China in 1998 and 2005. To determine the major risk factors and source of the infections, we analyzed whole genomes of 95 outbreak-associated isolates, identified 160 single nucleotide polymorphisms, and classified them into 6 clades. Molecular clock analysis revealed that clade 1 (responsible for the 1998 outbreak) emerged in October 1997. Clades 2-6 (responsible for the 2005 outbreak) emerged separately during February 2002-August 2004. A total of 41 lineages of S. suis emerged by the end of 2004 and rapidly expanded to 68 genome types through single base mutations when the outbreak occurred in June 2005. We identified 32 identical isolates and classified them into 8 groups, which were distributed in a large geographic area with no transmission link. These findings suggest that persons were infected in parallel in respective geographic sites.
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