Evidence map›Paper›PMID 27996064›Full record

ArticleWellcome open research2016

Free serum haemoglobin is associated with brain atrophy in secondary progressive multiple sclerosis.

Alex Lewin, Shea Hamilton, Aviva Witkover, Paul Langford, Richard Nicholas, Jeremy Chataway, Charles R M Bangham

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. A framework for blood biomarker discovery in MS.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026
    Review
  3. Article
  4. Review
  5. Mild Systemic Inflammation Increases Erythrocyte Fragility.International journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. IsMultiple sclerosis (Houndmills, Basingstoke, England) · 2023
    Review
  9. Proteomics in Multiple Sclerosis: The Perspective of the Clinician.International journal of molecular sciences · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Biodegradable nanofiber-based piezoelectric transducer.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Article
  17. Review
  18. MRI phenotypes in MS: Longitudinal changes and miRNA signatures.Neurology(R) neuroimmunology & neuroinflammation · 2019
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Alex Lewin *Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
Shea Hamilton *Division of Infectious Diseases, Department of Medicine, Imperial College London, London, UK.ORCID 0000-0001-6308-0253
Aviva WitkoverDivision of Infectious Diseases, Department of Medicine, Imperial College London, London, UK.
Paul LangfordDivision of Infectious Diseases, Department of Medicine, Imperial College London, London, UK.ORCID 0000-0002-6368-4724
Richard NicholasDivision of Brain Sciences, Department of Medicine, Imperial College London, London, UK.
Jeremy ChatawayNational Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust and Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, University College London, London, UK.
Charles R M BanghamDivision of Infectious Diseases, Department of Medicine, Imperial College London, London, UK.ORCID 0000-0003-2624-3599
Medical University of Graz · ATImperial College London · GBUniversity College London Hospitals NHS Foundation Trust · GB

Funding

Biotechnology and Biological Sciences Research Council BB/G000352/1Medical Research Council G1002319Medical Research Council MR/K019090/1Medical Research Council MR/M013138/1Wellcome Trust 100291
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brain atrophyhaemoglobinironneurodegenerationpathogenesisproteomicsSecondary progressive multiple sclerosis

Identifiers

PMID27996064
PMCPMC5159626
OpenAlexW2552054283

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.