Evidence map›Paper›PMID 27996028›Full record

ArticleScientific reports2016

High resolution 3D imaging of living cells with sub-optical wavelength phonons.

Fernando Pérez-Cota, Richard J Smith, Emilia Moradi, Leonel Marques, Kevin F Webb, Matt Clark

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Phonon imaging in 3D with a fibre probe.Light, science & applications · 2021
    Article
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  18. High-resolution analogue of time-domain phonon spectroscopy in the transmission electron microscope.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fernando Pérez-CotaOptics and photonics group, Faculty of Engineering, University of Nottingham,University Park, Nottingham, UK.
Richard J SmithOptics and photonics group, Faculty of Engineering, University of Nottingham,University Park, Nottingham, UK.
Emilia MoradiOptics and photonics group, Faculty of Engineering, University of Nottingham,University Park, Nottingham, UK.
Leonel MarquesOptics and photonics group, Faculty of Engineering, University of Nottingham,University Park, Nottingham, UK.
Kevin F WebbOptics and photonics group, Faculty of Engineering, University of Nottingham,University Park, Nottingham, UK.
Matt ClarkOptics and photonics group, Faculty of Engineering, University of Nottingham,University Park, Nottingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Label-free imaging of living cells below the optical diffraction limit poses great challenges for optical microscopy. Biologically relevant structural information remains below the Rayleigh limit and beyond the reach of conventional microscopes. Super-resolution techniques are typically based on the non-linear and stochastic response of fluorescent labels which can be toxic and interfere with cell function. In this paper we present, for the first time, imaging of live cells using sub-optical wavelength phonons. The axial imaging resolution of our system is determined by the acoustic wavelength (λ

Indexed as

Phonons3T3 CellsAnimalsCell LineImaging, Three-DimensionalMiceMicroscopyMicroscopy, AcousticSingle-Cell Analysis

Identifiers

PMID27996028
PMCPMC5171858

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.