Evidence map›Paper›PMID 27995987›Full record

ArticleScientific reports2016

Intrinsic Photosensitivity Enhances Motility of T Lymphocytes.

Thieu X Phan, Barbara Jaruga, Sandeep C Pingle, Bidhan C Bandyopadhyay, Gerard P Ahern

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
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  10. Antimicrobial blue light inactivation of pathogenic microbes: State of the art.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Thieu X PhanDepartment of Pharmacology and Physiology, Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington DC, 20007, USA.
Barbara JarugaDepartment of Pharmacology and Physiology, Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington DC, 20007, USA.
Sandeep C PingleDepartment of Pharmacology and Physiology, Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington DC, 20007, USA.
Bidhan C BandyopadhyayDepartment of Pharmacology and Physiology, Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington DC, 20007, USA.
Gerard P AhernDepartment of Pharmacology and Physiology, Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington DC, 20007, USA.
Georgetown University · USGeorgetown University Medical Center · USVeterans Health Administration · US

Funding

Calcium transport in kidney proximal tubule and calcium phosphate stone formationR01DK102043 · NIDDK · INSTITUTE FOR CLINICAL RESEARCH, INC. · PI BANDYOPADHYAY, BIDHAN CHANDRA · 2015 to 2019
$1.1M
NIDDK NIH HHS R01 DK102043
6 · The paper itself

Abstract

Sunlight has important biological effects in human skin. Ultraviolet (UV) light striking the epidermis catalyzes the synthesis of Vitamin D and triggers melanin production. Although a causative element in skin cancers, sunlight is also associated with positive health outcomes including reduced incidences of autoimmune diseases and cancers. The mechanisms, however, by which light affects immune function remain unclear. Here we describe direct photon sensing in human and mouse T lymphocytes, a cell-type highly abundant in skin. Blue light irradiation at low doses (<300 mJ cm

Indexed as

AnimalsCalciumCell MovementCell ProliferationChemotaxisHumansHydrogen PeroxideJurkat CellsMicePhospholipase C gammaPhosphorylationPhotonsRNA InterferenceSignal TransductionSkinSpleenCalciumHydrogen PeroxidePhospholipase C gamma

Identifiers

PMID27995987
PMCPMC5171715
OpenAlexW2567603875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.