Evidence map›Paper›PMID 27995751›Full record

ReviewAdvanced healthcare materials2017

3D Bioprinting for Organ Regeneration.

Haitao Cui, Margaret Nowicki, John P Fisher, Lijie Grace Zhang

Abstract readReview
In one paragraph

Review in Advanced healthcare materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 181 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
181citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

181 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Advances in Engineering Human Tissue Models.Frontiers in bioengineering and biotechnology · 2020
    Pooled it
  4. MXene Bioinks for 3D Bioprinting: Design and Translation.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
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121 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Haitao CuiDepartment of Mechanical and Aerospace Engineering, Department of Biomedical Engineering, Department of Medicine, The George Washington University, 3590 Science and Engineering Hall, 800 22nd Street NW, Washington, DC, 20052, USA.
Margaret NowickiDepartment of Mechanical and Aerospace Engineering, Department of Biomedical Engineering, Department of Medicine, The George Washington University, 3590 Science and Engineering Hall, 800 22nd Street NW, Washington, DC, 20052, USA.
John P FisherFischell Department of Bioengineering, University of Maryland, 3238 Jeong H. Kim Engineering Building, College Park, MD, 20742, USA.
Lijie Grace ZhangDepartment of Mechanical and Aerospace Engineering, Department of Biomedical Engineering, Department of Medicine, The George Washington University, 3590 Science and Engineering Hall, 800 22nd Street NW, Washington, DC, 20052, USA.

Funding

A Novel 3D Bioprinted Smart Vascularized Nano TissueDP2EB020549 · NIBIB · GEORGE WASHINGTON UNIVERSITY · PI ZHANG, LIJIE GRACE · 2014 to 2014
$2.3M
NIBIB NIH HHS DP2 EB020549
6 · The paper itself

Abstract

Regenerative medicine holds the promise of engineering functional tissues or organs to heal or replace abnormal and necrotic tissues/organs, offering hope for filling the gap between organ shortage and transplantation needs. Three-dimensional (3D) bioprinting is evolving into an unparalleled biomanufacturing technology due to its high-integration potential for patient-specific designs, precise and rapid manufacturing capabilities with high resolution, and unprecedented versatility. It enables precise control over multiple compositions, spatial distributions, and architectural accuracy/complexity, therefore achieving effective recapitulation of microstructure, architecture, mechanical properties, and biological functions of target tissues and organs. Here we provide an overview of recent advances in 3D bioprinting technology, as well as design concepts of bioinks suitable for the bioprinting process. We focus on the applications of this technology for engineering living organs, focusing more specifically on vasculature, neural networks, the heart and liver. We conclude with current challenges and the technical perspective for further development of 3D organ bioprinting.

Indexed as

Printing, Three-DimensionalRegenerationAnimalsHumansRegenerative Medicine3D bioprintingbiomaterialsneural regenerationorgan regenerationregenerative medicinevascularization

Identifiers

PMID27995751
PMCPMC5313259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.