Evidence map›Paper›PMID 27995492›Full record

ArticleJournal of materials science. Materials in medicine2017

Synthesis and characterization of PLGA/collagen composite scaffolds as skin substitute produced by electrospinning through two different approaches.

Ali Reza Sadeghi-Avalshahr, Mohammad Khorsand-Ghayeni, Samira Nokhasteh, Amir Mahdi Molavi, Hojjat Naderi-Meshkin

Abstract read
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In one paragraph

Article in Journal of materials science. Materials in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ali Reza Sadeghi-AvalshahrDepartment of Materials Research, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, Iran. sadeghi_alireza@jdm.ac.ir.
Mohammad Khorsand-GhayeniDepartment of Materials Research, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, Iran.
Samira NokhastehDepartment of Materials Research, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, Iran.
Amir Mahdi MolaviDepartment of Materials Research, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, Iran.
Hojjat Naderi-MeshkinStem Cell and Regenerative Medicine Research Department, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, Iran.
Academic Center for Education, Culture and Research · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin damage can occur for many reasons, including burns and injuries, which in extreme cases can even lead to death. Different methods such as electrospinning are used to produce scaffolds used in skin tissue engineering. Natural and synthetic polymers were used in this method. It was observed that the use of both natural and synthetic polymers gives better results for cell culturing rather than using of each material solely. In this study, scaffolds of poly(lactic-co-glycolic acid) and collagen were prepared using coating and common solvent methods. The characteristics of samples were evaluated through scanning electron microscopy, porosimetry, mechanical testing, degradation behavior, and in vitro assays. The mechanical and biocompatibility test results of the scaffold prepared by coating method were better than the other one. However, the degradation rate of the common solvent was nearly five times more than coating sample that leads to cytotoxicity in contact with the skin cells.

Indexed as

Skin, ArtificialBiocompatible MaterialsCell AdhesionCells, CulturedCollagenFibroblastsHumansKeratinocytesLactic AcidMicroscopy, Electron, ScanningPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerPorositySkinSolventsSpectroscopy, Fourier Transform InfraredBiocompatible MaterialsCollagenLactic AcidPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerSolventsCoatingsCollagenCommon solventElectrospinningPoly(lactic-co-glycolic acid)Skin tissue engineering

Identifiers

PMID27995492
OpenAlexW2565828493

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.