SynthesisHernia : the journal of hernias and abdominal wall surgery2017
Prophylactic mesh to prevent parastomal hernia after end colostomy: a meta-analysis and trial sequential analysis.
Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 7 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Comparing the effectiveness of prophylactic strategies for parastomal hernia prevention: a network meta-analysis.Techniques in coloproctology · 2025Pooled it
- Umbrella review of systematic reviews on the efficacy and safety of using mesh in the prevention of parastomal hernias.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- Parastomal hernia prevention with permanent mesh in end colostomy: failure with late follow-up of cohorts in three randomized trials.Hernia : the journal of hernias and abdominal wall surgery · 2023Pooled it
- Italian guidelines for the surgical management of enteral stomas in adults.Techniques in coloproctology · 2019Guideline
- Prophylactic mesh placement to avoid incisional hernias after stoma reversal: a systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2019Pooled it
- Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation.The Cochrane database of systematic reviews · 2019Pooled it
- Prosthetic mesh placement for the prevention of parastomal herniation.The Cochrane database of systematic reviews · 2018Pooled it
- Prevention of parastomal hernia after ileal conduit using prophylactic mesh: A meta-analysis of randomized controlled trials.Arab journal of urology · 2026Review
- Long-term outcome of prophylactic biosynthetic mesh reinforcement at the time of loop ileostomy reversal for colorectal cancer- results of a case-matched study.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Propensity Score Analysis of the Utility of Supervised Perioperative Abdominal Wall Exercises for the Prevention of Parastomal Hernia.Nursing reports (Pavia, Italy) · 2025Article
- Prophylactic Mesh in Parastomal Hernia Prevention: Current Evidence.Journal of abdominal wall surgery : JAWS · 2025Review
- A risk prediction model based on machine learning algorithm for parastomal hernia after permanent colostomy.BMC medical informatics and decision making · 2024Article
- Parastomal hernia prevention with an intraperitoneal prophylactic 3D-funnel mesh: review of the technique and middle-term results.Hernia : the journal of hernias and abdominal wall surgery · 2024Observational
- Prophylactic retromuscular mesh placement for parastomal hernia prevention: a retrospective cohort study of permanent colostomies and ileostomies.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- Synthetic Mesh in Contaminated Abdominal Wall Surgery: Friend or Foe? A Literature Review.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Review
- Abdominal Oblique Internal and External Muscles Gap Colostomy for Lower Incidence of Parastomal Hernia and Higher Quality of Life: A Retrospective Cohort Study.World journal of surgery · 2021Article
- Permanent end-colostomy parastomal hernia prevention using a novel three-dimensional mesh.Hernia : the journal of hernias and abdominal wall surgery · 2021Observational
- Preventing incisional ventral hernias: important for patients but ignored by surgical specialities? A critical review.Hernia : the journal of hernias and abdominal wall surgery · 2021Review
- Quality Assessment and Risk of Bias of Systematic Reviews of Prophylactic Mesh for Parastomal Hernia Prevention Using AMSTAR and ROBIS Tools.World journal of surgery · 2019Review
- Hernia prevention: practice patterns and surgeons' attitudes about abdominal wall closure and the use of prophylactic mesh.Hernia : the journal of hernias and abdominal wall surgery · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrevention of parastomal hernia (PSH) formation is crucial, given the high prevalence and difficulties in the surgical repair of PSH. To investigate the effect of a preventive mesh in PSH formation after an end colostomy, we aimed to meta-analyze all relevant randomized controlled trials (RCTs).
methodsWe searched five databases. For each trial, we extracted risk ratios (RRs) of the effects of mesh or no mesh. The primary outcome was incidence of PSH with a minimum follow-up of 12 months with a clinical and/or computed tomography diagnosis. RRs were combined using the random-effect model (Mantel-Haenszel). To control the risk of type I error, we performed a trial sequential analysis (TSA).
resultsSeven RCTs with low risk of bias (451 patients) were included. Meta-analysis for primary outcome showed a significant reduction of the incidence of PSH using a mesh (RR 0.43, 95% CI 0.26-0.71; P = 0.0009). Regarding TSA calculation for the primary outcome, the accrued information size (451) was 187.1% of the estimated required information size (RIS) (241). Wound infection showed no statistical differences between groups (RR 0.77, 95% CI 0.39-1.54; P = 0.46). PSH repair rate showed a significant reduction in the mesh group (RR 0.28 (95% CI 0.10-0.78; P = 0.01).
conclusionsPSH prevention with mesh when creating an end colostomy reduces the incidence of PSH, the risk for subsequent PSH repair and does not increase wound infections. TSA shows that the RIS is reached for the primary outcome. Additional RCTs in the previous context are not needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.