Evidence map›Paper›PMID 27995418›Full record

ArticleMolecular and cellular biochemistry2017

The effects of sildenafil citrate on urinary podocin and nephrin mRNA expression in an L-NAME model of pre-eclampsia.

Sooraj Baijnath, Saravanakumar Murugesan, Irene Mackraj, Prem Gathiram, Jagidesa Moodley

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Pre-eclampsia.Nature reviews. Disease primers · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Podocytes-The Most Vulnerable Renal Cells in Preeclampsia.International journal of molecular sciences · 2020
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sooraj BaijnathDepartment of Human Physiology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Saravanakumar MurugesanDepartment of Human Physiology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa. murugesans@ukzn.ac.za.
Irene MackrajDepartment of Human Physiology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa. mackraji@ukzn.ac.za.
Prem GathiramDepartment of Family Medicine, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
Jagidesa MoodleyDepartment of Obstetrics and Gynaecology and Women's Health and HIV Research Group, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the effects of sildenafil citrate (SC) on podocyturia in N

Indexed as

Pre-EclampsiaAnimalsDisease Models, AnimalFemaleGene Expression RegulationHumansIntracellular Signaling Peptides and ProteinsKidneyMembrane ProteinsNG-Nitroarginine Methyl EsterPregnancyRatsRats, Sprague-DawleyRNA, MessengerSildenafil CitrateIntracellular Signaling Peptides and ProteinsMembrane ProteinsnephrinNG-Nitroarginine Methyl EsterNPHS2 proteinRNA, MessengerSildenafil CitratePlGFPodocyturiaPre-eclampsiasFlt-1Sildenafil citrate

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.