Evidence map›Paper›PMID 27995369›Full record

Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2017

Responsiveness of SF-36 Health Survey and Patient Generated Index in people with chronic knee pain commenced on oral analgesia: analysis of data from a randomised controlled clinical trial.

Alex Papou, Salma Hussain, Daniel McWilliams, Weiya Zhang, Michael Doherty

Open access · greenAbstract readRandomized Controlled TrialValidation Study
PubMed Publisher
In one paragraph

Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Paracetamol versus placebo for knee and hip osteoarthritis.The Cochrane database of systematic reviews · 2019
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Alex PapouDepartment of Rheumatology, Queen's Medical Centre, Derby Road, Nottingham, NG7 2UH, UK.
Salma HussainFrimley Park Hospital, Portsmouth Road, Frimley, GU16 7UJ, UK.
Daniel McWilliamsDivision of Rheumatology, Orthopaedics and Dermatology, University of Nottingham, Academic Rheumatology, Clinical Sciences Building, Nottingham City Hospital, Hucknall Road, Nottingham, NG5 1PB, UK.
Weiya ZhangDivision of Rheumatology, Orthopaedics and Dermatology, University of Nottingham, Academic Rheumatology, Clinical Sciences Building, Nottingham City Hospital, Hucknall Road, Nottingham, NG5 1PB, UK. Weiya.Zhang@nottingham.ac.uk.
Michael DohertyDivision of Rheumatology, Orthopaedics and Dermatology, University of Nottingham, Academic Rheumatology, Clinical Sciences Building, Nottingham City Hospital, Hucknall Road, Nottingham, NG5 1PB, UK.
Nottingham City Hospital · GBFrimley Park Hospital · GBQueen's Medical Centre · GBUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose(1) To assess the responsiveness of the Short Form 36 Health Survey (SF-36) and Patient Generated Index (PGI) in people with knee pain who were given oral analgesics; and (2) to perform content analysis of the SF-36 and PGI aiming to identify differences between the instruments and causes of different responsiveness.

methodsAn observational study nested within a randomised controlled trial comparing oral paracetamol, ibuprofen or a combination of the two in 884 community-derived people with chronic knee pain. Each participant was given the SF-36 and PGI questionnaires to fill out at baseline, day 10, week 7 and week 13 after commencement on analgesia. Responsiveness was measured as a standardised response mean from baseline, and contents of the instruments were analysed.

resultsThe PGI showed the greater responsiveness to analgesics than the SF-36 throughout the study period. Only the Bodily Pain Score of the SF-36 showed comparable responsiveness to the PGI. The standardised response mean of the PGI at 13 weeks was 0.61 (95% CI 0.51-0.72), and that of the Bodily Pain Score of the SF-36 was 0.49 (95% CI 0.39-0.58). Content analysis of the PGI identified multiple areas which are not represented in the SF-36 which may help explain its performance.

conclusionsOverall the PGI is more responsive than the SF-36 to commonly used oral analgesics taken for knee pain. The PGI is able to elicit areas of individualised health-related quality of life which are not captured by the SF-36.

Indexed as

Quality of LifeAcetaminophenAnalgesics, Non-NarcoticFemaleHumansIbuprofenMaleMiddle AgedOsteoarthritis, KneePainPain MeasurementReproducibility of ResultsSurveys and QuestionnairesTreatment OutcomeAcetaminophenAnalgesics, Non-NarcoticIbuprofenHealth-related quality of lifeKnee painOsteoarthritisPatient Generated IndexResponsivenessSF-36

Identifiers

PMID27995369
OpenAlexW2562091154

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.