ArticleInternational journal of biometeorology2017
Expression dynamics of HSP70 during chronic heat stress in Tharparkar cattle.
Article in International journal of biometeorology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 66 citations in OpenAlex.
- Integrated Biological Responses Define the Thermoneutral Zone of Murrah Buffalo Calves in a Subtropical Climate.Animals : an open access journal from MDPI · 2026Article
- Mechanistic drivers of climate-induced reproductive collapse in African catfish: Multi-stressor interactions under IPCC scenarios.Journal of fish biology · 2026Article
- Genome-wide characterization of genetic diversity and breed discrimination markers in Tharparkar cattle.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- The blood transcriptome of musk deer under heat stress condition reveals the regulatory mechanism of genes to maintain homeostasis metabolism.BMC genomics · 2025Article
- Hungarian indigenous Tsigai, a promising breed for excellent heat tolerance and immunity.Saudi journal of biological sciences · 2023Article
- Expression profiling of heat shock protein genes in whole blood of Romosinuano cattle breed.Veterinary world · 2023Article
- The effect of heat stress on the cellular behavior, intracellular signaling profile of porcine growth hormone (pGH) in swine testicular cells.Cell stress & chaperones · 2022Article
- Thermoregulatory reactions of female buffaloes raised in the sun and in the shade, in the climatic conditions of the rainy season of the Island of Marajó, Pará, Brazil.Frontiers in veterinary science · 2022Article
- Remote ischemic preconditioning enhances aerobic performance by accelerating regional oxygenation and improving cardiac function during acute hypobaric hypoxia exposure.Frontiers in physiology · 2022Article
- Heat Stress: Effects on Rumen Microbes and Host Physiology, and Strategies to Alleviate the Negative Impacts on Lactating Dairy Cows.Frontiers in microbiology · 2022Review
- Glutamate Supplementation Improves Growth Performance, Rumen Fermentation, and Serum Metabolites in Heat-Stressed Hu Sheep.Frontiers in nutrition · 2022Article
- Long-term heat stress at final gestation: physiological and heat shock responses of Saanen goats.International journal of biometeorology · 2021Article
- Behavioural, physiological, neuro-endocrine and molecular responses of cattle against heat stress: an updated review.Tropical animal health and production · 2021Review
- Heat stress promotes lipid accumulation by inhibiting the AMPK-PGC-1α signaling pathway in 3T3-L1 preadipocytes.Cell stress & chaperones · 2021Article
- Dietary supplementation of dried plum: a novel strategy to mitigate heat stress in broiler chickens.Journal of animal science and biotechnology · 2021Article
- Heat stress in dairy animals and current milk production trends, economics, and future perspectives: the global scenario.Tropical animal health and production · 2021Review
- Climate-Resilient Dairy Cattle Production: Applications of Genomic Tools and Statistical Models.Frontiers in veterinary science · 2021Review
- Heat-Shock Proteins Gene Expression in Peripheral Blood Mononuclear Cells as an Indicator of Heat Stress in Beef Calves.Animals : an open access journal from MDPI · 2020Article
- Prospects of HSP70 as a genetic marker for thermo-tolerance and immuno-modulation in animals under climate change scenario.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2019Review
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Six male Tharparkar cattle aged 2-3 years were selected for the study. The animals were acclimatized in the psychrometric chamber at thermoneutral zone (TNZ) for 15 days and then exposed to 42 °C temperature up to 23 days followed by 12 days of recovery period. Physiological responses were estimated, and peripheral blood mononuclear cells (PBMCs) were isolated at TNZ on day 1, day 5, and day 12; after 6 h of heat stress exposure on day 16 to day 20, day 25, day 30, day 32, day 34, day 36, and day 38; and a recovery period on day 45 and day 50. The PBMCs were cultured to study the effect of thermal challenge on HSP70 messenger RNA (mRNA) expression pattern at different temperature-time combinations. The mRNA and protein expression of HSP70 in PBMCs along with serum extracellular HSP70 (eHSP70) was increased (P < 0.05) and showed two peaks on day 17 and day 32 (2nd and 17th days of thermal challenge, respectively). The HSP70 mRNA expression was increased (P < 0.05) in a temperature- and time-dependent manner in heat stress challenge treatment as compared to control in cultured PBMCs. HSP70 expression was found to be higher (P < 0.05) after 10 days of heat exposure (corresponds to chronic heat stress) as compared to the first 5 days of heat stress (corresponds to short-term heat stress) and control period at TNZ. The present findings indicate that HSP70 is possibly involved in heat stress adaptive response in Tharparkar cattle and the biphasic expression pattern may be providing a second window of protection during chronic heat stress.
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