Evidence map›Paper›PMID 27995315›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2017

A multidisciplinary systematic review of the treatment for chronic idiopathic tinnitus.

Hans-Peter Zenner, Wolfgang Delb, Birgit Kröner-Herwig, Burkhard Jäger, Ingrid Peroz, Gerhard Hesse, Birgit Mazurek, Gerhard Goebel, Christian Gerloff, Regina Trollmann and 3 more

Open access · greenAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 2 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 2 syntheses or guidelines pooled it, 153 citations in OpenAlex.

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  14. Levels of 25-hydroxyvitamin DFrontiers in neurology · 2025
    Article
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  16. Is Transcutaneous Electrical Nerve Stimulation Therapy the Answer for Tinnitus: A Prospective Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
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  20. Meteorological extremes and their impact on tinnitus-related emergency room visits: a time-series analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Hans-Peter ZennerDepartment of Otolaryngology, Head and Neck Surgery, University of Tübingen, Elfriede-Aulhorn-Str. 5, 72076, Tübingen, Germany. ut@hpzenner.de.
Wolfgang DelbOtorhinolaryngology Centre, Kaiserslautern, Germany.
Birgit Kröner-HerwigDepartment of Psychology, Georg-August University of Göttingen, Göttingen, Germany.
Burkhard JägerMental Health Centre, Clinic for Psychosomatics and Psychotherapy, Medical University of Hannover, Hannover, Germany.
Ingrid PerozDepartment for Dental Prosthetics, Geriatric Dentistry and Function, Charité Hospital, Medical School Berlin, Berlin, Germany.
Gerhard HesseTinnitus Clinic, Bad Arolsen Hospital, Arolsen, Germany.
Birgit MazurekCharité Hospital, Medical School Berlin, University Otorhinolaryngology Clinic, Berlin, Germany.
Gerhard GoebelDepartment of Behavioural Medicine, Psychosomatics, Psychiatry and Psychotherapy, Schön Clinic in Roseneck, Prien am Chiemsee, Germany.
Christian GerloffClinic and Outpatient Clinic for Neurology, University Hospital of Hamburg-Eppendorf, Hamburg, Germany.
Regina TrollmannSocial Paediatric Centre, Neuropaediatrics and Epileptology, University Paediatric Clinic, Erlangen, Germany.
Eberhard BiesingerOtorhinolaryngology Centre, Traunstein, Germany.
Harald SeidlerMedClin Bosenberg Clinics, Saint Wendel, Germany.
Berthold LangguthDepartment for Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Charité - Universitätsmedizin Berlin · DEMedizinische Hochschule Hannover · DEMSB Medical School Berlin · DESchön Klinik Roseneck · DEUniversitätsklinikum Erlangen · DEUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Göttingen · DEUniversity of Regensburg · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of tinnitus patients are affected by chronic idiopathic tinnitus, and almost 60 different treatment modalities have been reported. The present study is a multidisciplinary systematic analysis of the evidence for the different forms of treatment for chronic tinnitus. The results are used to form the basis of an S3 guideline. A systematic search was carried out in PubMed and the Cochrane Library. The basis for presenting the level of evidence was the evidence classification of the Oxford Centre of Evidence-based Medicine. Whenever available, randomised controlled trials were given preference for discussing therapeutic issues. All systematic reviews and meta-analyses were assessed for their methodological quality, and effect size was taken into account. As the need for patient counselling is self-evident, specific tinnitus counselling should be performed. Due to the high level of evidence, validated tinnitus-specific, cognitive behavioural therapy is strongly recommended. In addition, auditory therapeutic measures can be recommended for the treatment of concomitant hearing loss and comorbidities; those should also be treated with drugs whenever appropriate. In particular, depression should be treated, with pharmacological support if necessary. If needed, psychiatric treatment should also be given on a case-by-case basis. With simultaneous deafness or hearing loss bordering on deafness, a CI can also be indicated. For auditory therapeutic measures, transcranial magnetic or direct current stimulation and specific forms of acoustic stimulation (noiser/masker, retraining therapy, music, and coordinated reset) for the treatment of chronic tinnitus the currently available evidence is not yet sufficient for supporting their recommendation.

Indexed as

TinnitusAcoustic StimulationCognitive Behavioral TherapyDiagnosis, DifferentialDisease ManagementElectric Stimulation TherapyHearing LossHumansCochlear implantCognitive behavioural therapyDrug therapyRetraining therapyTinnitus

Identifiers

PMID27995315
OpenAlexW2561335613

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.