ArticleTurkish journal of emergency medicine2016
Electrocardiographic changes in patients with tramadol-induced idiosyncratic seizures.
Article in Turkish journal of emergency medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Harmful Effects of Prescribed Opioids in Children and Adults: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- The Relationship Between Tramadol Use and Cardio Electrophysiological Balance for Postoperative Pain Treatment in General Surgery Patients.Medicina (Kaunas, Lithuania) · 2024Article
- Effects of opioid receptor agonist and antagonist medications on electrocardiogram changes and presentation of cardiac arrhythmia: review article.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022Review
- Potential Impact of 3% Hypertonic Saline Infusion on Tramadol Poisoning-Induced Electrocardiogram Changes; a Randomized Clinical Trial.Archives of academic emergency medicine · 2022Article
- Low-Dose Tramadol as an Off-Label Antidepressant: A Data Mining Analysis from the Patients' Perspective.ACS pharmacology & translational science · 2020Article
- Ecotoxicity screening evaluation of selected pharmaceuticals and their transformation products towards various organisms.Environmental science and pollution research international · 2020Article
- Seizure Prediction Model in Acute Tramadol Poisoning; a Derivation and Validation study.Archives of academic emergency medicine · 2020Article
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Authors and funding
7 authors.
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Abstract
objectivesTo assess ECG changes in patients with tramadol-induced seizure(s) and compare these changes in lower and higher than 500 mg tramadol doses as a main goal. MATERIAL AND
methodsIn an analytical-cross sectional manner over 1 year, 170 patients with idiosyncratic seizure(s) after using tramadol, were studied. Full data were recorded for each patient. ECGs were taken from all the patients on admission and 1 h later and were assessed for findings.
results70 of 170 patients (41.2%) had used lower than 500 mg doses of tramadol while 90 patients (52.9%) were included in the high dose group. Rate of female patients in the high dose group was significantly higher. The average age of patients in the high dose group was significantly lower (22.04 vs 25.76). The high dose group had significantly higher heart rates. There was no history of cardiovascular diseases; two patients had previous history of seizure. No significant difference was shown between low dose and high dose groups from the point of ECG changes. DISCUSSION AND
conclusionUsing doses higher than 500 mg is more frequently seen in women, young people and those who have not experienced previous use of tramadol. Terminal S wave, sinus tachycardia, and terminal R wave in the lead aVR are among the most common ECG changes in tramadol users.
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