Evidence map›Paper›PMID 27995096›Full record

ArticleFrontiers in cellular and infection microbiology2016

The Amino-Terminal Part of the Needle-Tip Translocator LcrV of

Sofie Ekestubbe, Jeanette E Bröms, Tomas Edgren, Maria Fällman, Matthew S Francis, Åke Forsberg

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sofie EkestubbeLaboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå UniversityUmeå, Sweden; Department of Molecular Biology, Umeå Centre for Microbial Research, Umeå UniversityUmeå, Sweden.
Jeanette E BrömsDepartment of Clinical Microbiology, Umeå University Umeå, Sweden.
Tomas EdgrenDepartment of Molecular Biology, Umeå Centre for Microbial Research, Umeå University Umeå, Sweden.
Maria FällmanLaboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå UniversityUmeå, Sweden; Department of Molecular Biology, Umeå Centre for Microbial Research, Umeå UniversityUmeå, Sweden.
Matthew S FrancisDepartment of Molecular Biology, Umeå Centre for Microbial Research, Umeå University Umeå, Sweden.
Åke ForsbergLaboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå UniversityUmeå, Sweden; Department of Molecular Biology, Umeå Centre for Microbial Research, Umeå UniversityUmeå, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type III secretion systems (T3SS) are dedicated to targeting anti-host effector proteins into the cytosol of the host cell to promote bacterial infection. Delivery of the effectors requires three specific translocator proteins, of which the hydrophilic translocator, LcrV, is located at the tip of the T3SS needle and is believed to facilitate insertion of the two hydrophobic translocators into the host cell membrane. Here we used

Indexed as

AnimalsAntigens, BacterialBacterial Outer Membrane ProteinsMacrophagesMicePhagocytosisPore Forming Cytotoxic ProteinsProtein TransportProtein Tyrosine PhosphatasesVirulenceVirulence FactorsYersinia pseudotuberculosisAntigens, BacterialBacterial Outer Membrane ProteinsLcrV protein, YersiniaPore Forming Cytotoxic ProteinsProtein Tyrosine PhosphatasesVirulence FactorsyopH protein, YersiniaLcrVpore formationtranslocationtype III secretion systemvirulenceYersinia pseudotuberculosisYopH

Identifiers

PMID27995096
PMCPMC5136540

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.