Evidence map›Paper›PMID 27995073›Full record

ArticleNeuroImage. Clinical2017

Distinct effects of childhood ADHD and cannabis use on brain functional architecture in young adults.

Clare Kelly, F Xavier Castellanos, Olivia Tomaselli, Krista Lisdahl, Leanne Tamm, Terry Jernigan, Erik Newman, Jeffery N Epstein, Brooke S G Molina, Laurence L Greenhill and 4 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Exploring the Link Between Attention-Deficit Hyperactivity Disorder and Cannabis Use Disorders: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Clare KellySchool of Psychology, Trinity College Dublin, Dublin, Ireland; Department of Psychiatry, School of Medicine, Trinity College Dublin, Dublin, Ireland; Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland; Center for Neurodevelopmental Disorders, Child Study Center, New York University Langone Medical Center, New York, NY, USA.
F Xavier CastellanosCenter for Neurodevelopmental Disorders, Child Study Center, New York University Langone Medical Center, New York, NY, USA; Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Olivia TomaselliCenter for Neurodevelopmental Disorders, Child Study Center, New York University Langone Medical Center, New York, NY, USA; National Adoption & Fostering Team, Michael Rutter Center, Maudsley Hospital, London, UK.
Krista LisdahlUniversity of Wisconsin-Milwaukee, Psychology Department, 2441 E. Hartford Ave, Milwaukee, WI, USA.
Leanne TammCincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, ML10006 Cincinnati, OH, USA.
Terry JerniganCenter for Human Development, University of California, San Diego, La Jolla, CA, USA; Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.
Erik NewmanCenter for Human Development, University of California, San Diego, La Jolla, CA, USA.
Jeffery N EpsteinDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Brooke S G MolinaDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.
Laurence L GreenhillDepartment of Psychiatry, Columbia University, New York, NY, USA.
Steven G PotkinDepartment of Psychiatry and Human Behavior, School of Medicine, University of California Irvine, Irvine, CA, USA.
Stephen HinshawDepartment of Psychology, University of California-Berkeley, Berkeley, CA, USA.
James M SwansonChild Development Center, University of California, Irvine, Irvine, CA, USA.
MTA Neuroimaging Group

Funding

IDEAA: UWM SiteR01DA030354 · NIDA · UNIVERSITY OF WISCONSIN MILWAUKEE · PI LISDAHL, KRISTA MAURINE · 2011 to 2017
$2.7M
Pathways to adult substance use and abuse from childhood ADHD in the MTAR01DA039881 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 2015 to 2018
$1.1M
Validity and Reliability of New Standard for Resting fMRI DataR03MH104334 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KELLY, ANNE MARIE CLARE · 2014 to 2015
$170k
NIDA NIH HHS HHSN271200800009CNIDA NIH HHS R01 DA030354NIDA NIH HHS R01 DA039881NIMH NIH HHS R03 MH104334
6 · The paper itself

Abstract

One of the most salient long-term implications of a childhood diagnosis of ADHD is an increased risk for substance use, abuse, or dependence in adolescence and adulthood. The extent to which cannabis use affects ADHD-related alterations in brain functional organization is unknown, however. To address this research gap, we recruited a sample of 75 individuals aged 21-25 years with and without a childhood diagnosis of ADHD Combined Type, who were either frequent users or non-users of cannabis. These participants have been followed longitudinally since age 7-9.9 years as part of a large multi-site longitudinal study of ADHD, the Multimodal Treatment Study of Children with ADHD (MTA). We examined task-independent intrinsic functional connectivity (iFC) within 9 functional networks using a 2 × 2 design, which compared four groups of participants: (1) individuals with a childhood diagnosis of ADHD who currently use cannabis (

Indexed as

CannabisAdultAttention Deficit Disorder with HyperactivityConnectomeExecutive FunctionFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMalePsychomotor PerformanceYoung AdultADHDCannabisfMRIFunctional connectivityMarijuanaNeurocognitive

Identifiers

PMID27995073
PMCPMC5153452

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.