Evidence map›Paper›PMID 27995058›Full record

ArticleRespiratory medicine case reports2017

Erdheim-Chester disease, moving away from the orphan diseases: A case report.

Jessica M Stempel, Jean G Bustamante Alvarez, Andres Mora Carpio, Varun Mittal, Claudia Dourado

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Role ofThe Indian journal of radiology & imaging · 2021
    Article
  4. European journal of nuclear medicine and molecular imaging · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jessica M StempelAlbert Einstein Medical Center, Department of Internal Medicine, Philadelphia, PA, USA.
Jean G Bustamante AlvarezAlbert Einstein Medical Center, Department of Internal Medicine, Philadelphia, PA, USA.
Andres Mora CarpioAlbert Einstein Medical Center, Department of Internal Medicine, Philadelphia, PA, USA.
Varun MittalAlbert Einstein Medical Center, Department of Internal Medicine, Philadelphia, PA, USA; Albert Einstein Medical Center, Department of Hematology and Oncology, Philadelphia, PA, USA.
Claudia DouradoAlbert Einstein Medical Center, Department of Internal Medicine, Philadelphia, PA, USA; Albert Einstein Medical Center, Department of Hematology and Oncology, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With approximately 750 cases reported, Erdheim-Chester disease is an exceedingly rare histiocyte cell disorder. Affected sites typically include long bones, large vessels and central nervous system. However, cutaneous and pulmonary involvement can also occur. The diagnosis is ascertained by identification of foamy histiocytes positive for CD68, CD163, and factor XIIIa on immunoperoxidase staining. Recently published literature have described an association between Erdheim-Chester disease and BRAF V600E mutation. This finding prompted the investigation of therapeutic possibilities with BRAF inhibitors, successful agents against other

Indexed as

BRAF V600E mutationErdheim-Chester diseaseVemurafenib

Identifiers

PMID27995058
PMCPMC5153444

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.