Evidence map›Paper›PMID 27994959›Full record

ArticlePeerJ2016

RNA interference as a gene silencing tool to control

Roberto A Camargo, Guilherme O Barbosa, Isabella Presotto Possignolo, Lazaro E P Peres, Eric Lam, Joni E Lima, Antonio Figueira, Henrique Marques-Souza

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. TransformingInsects · 2025
    Review
  5. Article
  6. Harnessing double-stranded RNA (dsRNA): a sustainable approach to pest management.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Stabilized Double-Stranded RNA Strategy Improves Cotton Resistance to CBW (International journal of molecular sciences · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Chromatin-Remodelling ATPasesInternational journal of molecular sciences · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Roberto A CamargoCentro de Energia Nuclear na Agricultura, Universidade de São Paulo, Piracicaba, São Paulo, Brazil; Escola Superior de Agricultura "Luiz de Queiroz" (ESALQ), Universidade de São Paulo, Piracicaba, São Paulo, Brazil.
Guilherme O BarbosaDepartamento de Bioquímica e Biologia Tecidual, Universidade Estadual de Campinas , Campinas , São Paulo , Brazil.
Isabella Presotto PossignoloCentro de Energia Nuclear na Agricultura, Universidade de São Paulo, Piracicaba, São Paulo, Brazil; Escola Superior de Agricultura "Luiz de Queiroz" (ESALQ), Universidade de São Paulo, Piracicaba, São Paulo, Brazil.
Lazaro E P PeresEscola Superior de Agricultura "Luiz de Queiroz" (ESALQ), Universidade de São Paulo , Piracicaba , São Paulo , Brazil.
Eric LamDepartment of Plant Biology & Pathology, Rutgers, The State University of New Jersey , New Brunswick , NJ , United States.
Joni E LimaCentro de Energia Nuclear na Agricultura, Universidade de São Paulo, Piracicaba, São Paulo, Brazil; Departamento de Botânica, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Antonio FigueiraCentro de Energia Nuclear na Agricultura, Universidade de São Paulo , Piracicaba , São Paulo , Brazil.
Henrique Marques-SouzaDepartamento de Bioquímica e Biologia Tecidual, Universidade Estadual de Campinas , Campinas , São Paulo , Brazil.
Universidade de São Paulo · BRUniversidade Estadual de Campinas (UNICAMP) · BRRutgers, The State University of New Jersey · USUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA interference (RNAi), a gene-silencing mechanism that involves providing double-stranded RNA molecules that match a specific target gene sequence, is now widely used in functional genetic studies. The potential application of RNAi-mediated control of agricultural insect pests has rapidly become evident. The production of transgenic plants expressing dsRNA molecules that target essential insect genes could provide a means of specific gene silencing in larvae that feed on these plants, resulting in larval phenotypes that range from loss of appetite to death. In this report, we show that the tomato leafminer (

Indexed as

Agro-infiltrationdsRNA deliverydsRNA uptakeGene silencingMicro-tomPest controlRNAiTransgenicTuta absoluta

Identifiers

PMID27994959
PMCPMC5162399
OpenAlexW2517358831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.